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Öğe Aerobic and anaerobic exercise performance in female patients with fibromyalgia: Effects of antidepressants(FEDERATION AMER SOC EXP BIOL, 2005) Okudan, Nilsel; Özerbil, O. M.; Gökbel, Hakkı; Levendoğlu, F[Abstract not Available]Öğe Comparison of Phenol and Alcohol Neurolysis of Tibial Nerve Motor Branches to the Gastrocnemius Muscle for Treatment of Spastic Foot After Stroke: A Randomized Controlled Pilot Study(Edizioni Minerva Medica, 2010) Kocabaş, H.; Sallı, A.; Demir, A. H.; Özerbil, O. M.Aim. The aim of this paper was to determine whether the injection of alcohol or phenol into the tibialis posterior nerve relive the symptoms and signs of ankle plantar flexor spasticity. Methods. Twenty patients with hemiplegic stroke were included. Patients were randomly assigned to receive a single treatment of alcohol or phenol injection to the motor branches of tibial nerve. Clinical outcome parameters were measured before Motor branch block, immediately, and at 1, 3, and 6 months after blocking. These parameters included a. Ankle plantar flexor spasticity assessed by Modified Ashworth Scale, b. Clonus of the ankle; c. The passive range of motion changes measured by goniometer and d. Motor strength of the ankle plantar flexors measured by the Medical Research Council grades 0-5. Results. In the alcohol group the spasticity score for the ankle plantar flexor was reduced in all 10 patients immediately after motor branch block and this was maintained over the 6 month follow up period in 9 patients. In the phenol group the spasticity score for the ankle plantar flexor was reduced in all 10 patients immediately after motor branch block and it was maintained over the 6 month follow up period in 7 patients. Conclusion. It was observed that both two methods are effective in reducing spasticity however the use of 50% alcohol as a neurolytic agent in the management of ankle plantar flexor spasticity appears to be long lasting method of regional spasticity treatment.Öğe The Efficacy of Carbamazepine in the Treatment of the Pain Due to Lumbar Lateral Canal Stenosis(1997) Üstün, M. E.; Özerbil, O. M.; Güney, O.; Kocaoğullar, Y.In this study, we investigated whether carbamazepine which usually is used in many diseases characterized by neuropathy or neuralgia to reduce pain, has an analgesic effect in patients with lateral canal stenosis. 14 patients (7 women, 7 men) with lateral canal stenosis whose age ranged between 32 and 74 were included in the study. These patients had low back pain and/or sciatica at least for six months and they didn't respond to other medical drugs including nonsteroidal antiinflammatory drugs and analgesics. They were administered 400 mg/bid oral carbamazepine as initial dose for two weeks. When they didn't respond to that dose, it was increased to 800 mg/bid for four weeks. The patients pain were evaluated by the leg pain severity and overall functional disability score before and after treatment. After treatment, the pain was significantly reduced in these patients (p < 0.01, X2:10). In conclusion, we propose carbamazepine in the treatment of lateral canal stenosis as a new alternative drug.Öğe Epidural Administration of Midasolam for Chronic Central Pain and Spasticity in Spinal Cord Injured Patients(1997) Özerbil, O. M.; Duman, A.; Yosunkaya, A.; Bayram, A.; Üstün, M. E.In the patients with spinal cord injury (SCI) chronic pain and spasticity affect significantly both the efficacy of rehabilitation and the quality of life. Recently it was shown that intrathecally and epidurally administered midasolam has analgesic and antispatic effects in both animals and humans so that it constitutes an alternative to be used in patients with SCI. In this study, four paraplegics who suffered from chronic central pain and spasticity in their lower extremities were given midasolan 6 times daily (dose 40 ?g/kg dose dissolved in 10 ml normal saline) via lumbar epidural catheter using pain management provider. Spasticity was monitored by means of a modified Ashwort scale, and pain evaluation was performed by face scale and VAS. The patients were hospitalized at least for two weeks and were observed for the efficacy of the drug. Although epidural administration of midasolam relieved both central pain and spasticity, it's efficacy on central pain was more pronounced. There were no significant side effects is any patient. We propose that midasolam may be given by epidural catheter or implantable drug pump for the treatment of central pain and/or spinal spasticity in spinal cord injured patients.Öğe The Utility of Dermatomal Somatosensory Evoked Potentials (Dseps) in Diagnosis and Prognosis of The Unilateral Lumbosacral Radiculopathy Due to Herniated Intervertebral Disc(1995) Özerbil, O. M.; Demir, O.; Oğuz, H.; Genç, B. O.; Yel, M.In this study, determination of the utility of DSEPs in patients with unilateral lumbosacral radiculopathy due to herniated intervertebral disc for diagnosing, planning the management and obtaining information about prognosis was purposed. Scalp-recorded somatosensory evoked potentials to electrical stimulation in L5 and S1 dermatomes in 31 patients and 26 normal subjects were examined. Abnormal DSEP recordings were obtained by comparing with normal values derived from studies of normal subjects. DSEP recordings were compared with the results of computed tomography and electromyographic studies of the same patients. All of the patients had conservative therapy, and physical examination and DSEP studies of 23 patients were reevaluated after three months and improvement of the clinical and DSEP findings were compared in each patient. DSEP sensitivity of 31 patients is 77.4 %. Absent responses were associated with acute lesions and with low back pain in extension. DSEP findings after three months perfectly reflected either clinical improvement or continuation of symptoms and clinical findings. It was concluded that, (1) there is no superiority of DSEP to the other studies in identifying unilateral lumbosacral radiculopathy due to herniated intervertebral disc, if technical and interpretational differences are removed, diagnostic utility of DSEPs will increase (2) DSEPs have a prognostic utility to follow the patients' courses.
