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Öğe Effect of Different Finishing Techniques for Restorative Materials on Surface Roughness and Bacterial Adhesion(MOSBY-ELSEVIER, 2010) Aykent, Filiz; Yöndem, İsa; Özyeşil, Atilla G.; Günal, Şölen K.; Avunduk, Mustafa C.; Özkan, SemihaStatement of problem. The formation of biofilm and bacterial accumulation on dental materials may lead to the development of gingival inflammation and secondary caries. Purpose. The purpose of this study was to examine the effect of different surface finishing and polishing methods on surface roughness and the adhesion of S. mutans bacteria to 2 new-generation indirect composite resins, 1 direct composite resin, and 1 ceramic material. Material and methods. Forty specimens (10 x 10 x 2 mm) of each material, indirect composite resins (SR Adoro, Estenia), direct composite resin (Tetric), and a ceramic material (VITABLOCS Mark II), were fabricated. Specimens were divided into 4 groups (n=10) that were treated with 1 of the following 4 surface finishing techniques: diamond rotary cutting instrument, sandpaper discs (Sof-Lex), silicone-carbide rubber points (Shofu), or a felt wheel with diamond paste. Surface roughness was measured with a profilometer. Test specimens were covered with artificial saliva and mucin to produce pellicle. Bacterial suspension (10(9) CFU/ml) was then added to the pellicle-coated specimens, and bacterial adhesion was determined using a confocal laser microscope and image analyzing program. Data were analyzed with 2-way ANOVA, followed by Tukey HSD test, Pearson correlation, and regression analysis (alpha=.05). Results. The highest surface roughness values were recorded in SR Adoro and diamond rotary cutting instrument groups. The lowest vital S. mutans adhesion was seen in the ceramic group and in SR Adoro indirect composite resin (P<.05). Conclusions. Bacterial adhesion to indirect composite resin materials differed from that to ceramic material after surface treatments. A positive correlation was observed between surface roughness and the vital S. rnutans adhesion.Öğe Effects of Recombinant Human Erythropoietin on Mandibular Distraction Osteogenesis(W B SAUNDERS CO-ELSEVIER INC, 2009) Mihmanli, Ahmet; Dolanmaz, Dogan; Avunduk, Mustafa C.; Erdemli, EsraPurpose: To evaluate the effects of subcutaneous administration of recombinant human erythropoietin (rHuEPO) oil regeneration formation and quality during mandibular distraction osteogenesis. Materials and Methods: Sixteen adult male New Zealand rabbits were Used ill this study Ethical approval was obtained front the Animal Research Institute of Selcuk University, Konya, Turkey Subjects were randomly divided into 2 groups Distraction osteogenesis (DO) was performed witha Custom-made distractor on the left mandibles of rabbits. In the experimental group, 4 doses of 150 IU/kg rHuEPO wet-administered at 48-hour intervals. The first close was given immediately after surgery. Control subjects received 0 5 mL/kg isotonic solution in the same manner After 2 clays of latency, mandibles were distracted I mm/day at 12-hour intervals for 5 clays. A 5-mm lengthening was achieved. All animals were sacrificed after 30 days of consolidation Afterward, samples were prepared for histomorphometric evaluation of newly formed bone area. Results: The number of osteoblasts and blood vessels was significantly higher, whereas the number of osteoclasts was significantly lower, ill the experimental group than in the control group (P < 05) In the experimental group. the area of new bone formation was greater than in the control group (P < .05). Moreover. fibroblast and collagen numbers per Unit area were higher in the experimental group However, this finding was not statistically significant (P > 05) Conclusion: The subcutaneous administration of rHuEPO improves the rate and quality of bone-healing during distraction osteogenesis. However, the short-term favorable effects of rHuEPO in tills study should be extended with long-term investigations before clinical application. (C) 2009 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 67-2337-2343, 2009Öğe Morphologic alteration induced by short-term smoke exposure in rats(KARGER, 2007) Isik, A. Cemal Umit; Yardimci, Serdar; Guven, Cengiz; Avunduk, Mustafa C.; Civelek, SenolBackground: It is a well-established fact that cigarette smoking causes degenerative, inflammatory, and respiratory diseases in humans. Because many factors such as air pollution and harsh working conditions can easily be eliminated in animal studies, we conducted this study to identify the effect of tobacco on rat trachea. Methods: 24 male Wistar rats were divided randomly into an experimental and a control group. The experimental group of rats was exposed to cigarette smoke for 2 h each day over a duration of 60 consecutive days and the control group was treated in an identical fashion yet exposed only to room air. A morphometric study was performed on tracheal specimens taken from 22 rats (10 smoke-exposed rats and 12 control rats). Results: Our results show that many of the morphological changes of the tracheal epithelium were found in the experimental group and significant quantitative differences were observed between the two groups. Loss of cilia, basal cell hyperplasia, goblet cell hyperplasia and an increased number of subepithelial inflammatory cells were observed by light microscopic examination of the trachea of experimental rats. We found very high levels of plasma thiocyanate after exposure to smoke in the experimental group, but no increase in the control group. Conclusions: The oxidants contained tobacco which could play an important role in the development of these structural and functional abnormalities in the trachea after smoke exposure. In addition, smoking can recruit inflammatory cells to the trachea.Öğe Simultaneous occurrence of facial fibrous dysplasia and ameloblastoma(CHURCHILL LIVINGSTONE, 2009) Keskin, Mustafa; Karabekmez, Furkan E.; Ozkan, Birkan T.; Tosun, Zekeriya; Avunduk, Mustafa C.; Savaci, NedimBackground: Both fibrous dysplasia (FD) and ameloblastoma are benign but locally aggressive tumours of the cramofacial region. In this case report, we present the unique synchronous occurrence of these two tumours in the facial skeleton. Case report: A 16-year-old woman presented with complaints of swelling of the upper right face and at the inferior border of the mandible. She was diagnosed as FD of the maxilla, temporal bone and sphenoid sinus together with ameloblastoma of the mandible after surgery and histopathological evaluation. Conclusion: The case that we present here is unique in that two separate pathological conditions, FD of the upper face, and ameloblastoma of the mandible coexisted. Although cases of synchronous or metachronous occurrence of FD and ameloblastoma with other pathology have been previously described, this to our knowledge, is the first reported case of true coexistence of FD and ameloblastoma. (c) 2008 European Association for Cranio-Maxillofacial Surgery
