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Öğe Mikozis Fungoides Tedavisi Sırasında Ortaya Çıkan Skabies: Dermatoskopik Tanı(Turkish Society of Hematology, 2012) Aykol, Caner; Mevlitoğlu, İnci; Tol, Hüseyin; Uçar Tavlı, YelizScabies is a cutaneous infestation caused by Sarcoptes scabiei var. hominis and characterized by severe and generalized pruritus. A clinical diagnosis can be made when a burrow is detected at a typical predilection site and the lesion is severely itching. Scabies which occurs in the elderly and also in patients who are immunosuppressed, the lesions are very variable and clinical diagnosis may be difficult. In such cases, dermatoscopy is a simple and rapid diagnostic tool for the diagnosis of scabies with high sensitivity and specificity. Here, a 61-year-old woman who was diagnosed as scabies with dermatoscopic findings and already had mycosis fungoides is reported.Öğe Progresif maküler hipomelanozis(2011) Mevlitoğlu, İnci; Aykol, CanerProgresif maküler hipomelanozis (PMH) ilk olarak 1988 yılında Guillet tarafından tanımlanmıştır. PMH sıklıkla gövdeyi tutan, asemptomatik, zor fark edilen, numuler, skuamsız, hipopigmente makûllerle karakterizedir. PMH çoğunlukla adölesan ve genç kadınlarda görülür. Etyopatogenezi hala bilinmemektedir. Wood lambası altında hipopigmente makûllerde kırmızı foliküler flo-rasan görünürken komşu normal deride florasan gözlenmez. PMH'nin histopatolojik bulguları genellikle non-spesifiktir, ancak hipopigmente makûllerin melanin içeriğinin normal deriye göre azalmış olması sık görülen bir bulgudur. Etkili bir tedavi halen bilinmemektedir. Ancak fototerapi PMH'yi kontrol altına almada etkili bulunmuş olmasına karşın hastalığın rekürrensini önlememektedir. Biz bu makalede PMH'nin etyopatogenezi, klinik bulguları, histopatolojisi, ayırıcı tanısı ve tedavi seçeneklerini derlemeyi amaçladık. (Türkderm 2011; 45: 62-5)Öğe Progressive Macular Hypomelanosis(DERI ZUHREVI HASTALIKLAR DERNEGI, 2011) Mevlitoglu, Inci; Aykol, CanerProgressive macular hypomelanosis (PMH) was initially described and named by Guillet in 1988. PMH is characterized by asymptomatic, ill-defined, nummular, non-scaly, hypopigmented macules, localized predominantly on the trunk. PMH is mostly seen in adolescents and young females. The etiopathogenesis of PMH is still unknown. The red follicular fluorescence becomes visible in the hypopigmented macules under Wood's lamp but is absent in normal adjacent skin. The histopathologic findings in PMH are usually non-specific, but a common feature is the decreased melanin content in the hypopigmented macules compared to the normal skin. No effective therapy is currently known. Phototherapy was found to be effective for the control of PMH; however, it does not prevent recurrence of the disease. In this paper, we aimed to review the etiopathogenesis, clinical findings, histopathology, differential diagnosis and treatment options of PMH.