Yazar "Aykul, Fatmanur" seçeneğine göre listele

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    Biocompatible yogurt carbon dots: evaluation of utilization for medical applications
    (SPRINGER, 2017) Dinç, Saliha; Kara, Meryem; Kars, Meltem Demirel; Aykul, Fatmanur; Çiçekci, Hacer; Akkuş, Mehmet
    In this study, carbon dots (CDs) were produced from yogurt, a fermented milk product, via microwave-assisted process (800 W) in 30 min without using any additional chemical agents. Yogurt CDs had outstanding nitrogen and oxygen ratios. These dots were monodisperse and about 2 nm sized. The toxicological assessments of yogurt carbon dots in human cancer cells and normal epithelial cells and their fluorescence imaging in living cell system were carried out. Yogurt carbon dots had intense fluorescent signal under confocal microscopy and good fluorescence stability in living cell system. The resulting yogurt carbon dots exhibited high biocompatibility up to 7.1 mg/mL CD concentration which may find utilization in medical applications such as cellular tracking, imaging and drug delivery. Yogurt carbon dots have potential to be good diagnostic agents to visualize cancer cells which may be developed as a therapeutic carrier.
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    Hydrophobic coating of surfaces by plasma polymerization in an RF plasma reactor with an outer planar electrode: synthesis, characterization and biocompatibility
    (IOP PUBLISHING LTD, 2017) Karaman, Mustafa; Gursoy, Mehmet; Aykul, Fatmanur; Tosun, Zahide; Kars, M. Demirel; Yildiz, H. Bekir
    This paper presents the plasma polymerization of poly(hexafluorobutyl acrylate) (PHFBA) thin films on different substrates in an RF plasma reactor with an outer planar electrode. This reactor configuration allows. large area uniformity and fast processing times. Deposition rates of up to 60 nm min(-1) were observed. The influence. of plasma power and substrate temperature on the. deposition rate, structure and wettability of the as-deposited films was. investigated. It was observed that better hydrophobicity was obtained at high plasma power and in low temperature conditions. PHFBA thin films deposited on electrospun poly(acrylonitrile) fiber mats under such conditions resulted in superhydrophobic surfaces with. contact angle values greater than 150 degrees. In. vitro cell studies using human epithelial cells demonstrated the non-toxic nature of the. plasma-polymerized PHFBA films.