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Öğe Effect of Training and Gender on Plasma Irisin, Leptin, and Insulin Levels(INT JOURNAL APPLIED EXERCISE PHYSIOLOGY, 2018) Arikan, S.; Revan, S.; Balci, S. S.; Sahin, M.; Serpek, B.The objective of this study is the comparison of the irisin, leptin, and insulin hormone levels of the female and male elite athletes and non-athletes. Elite taekwondo athletes (7 males, 6 females) and university students (8 males, 6 females) between the ages of 16 and 20 years volunteered to participate in this study. In the beginning of the study, the body compositions of the participants were determined and their plasma irisin, leptin, and insulin hormone analyses were determined by the Enzyme-Linked Immuno Sorbent Assay (ELISA) method. After an overnight fast, the blood samples were collected at 8:00 a.m. A two-way ANOVA was performed to examine the effects of gender and training status. There was found no significant main and/or interaction effect of training and gender on the irisin and insulin hormone levels (p>0,05). However, training and gender affected the leptin levels significantly (p<0.05). The leptin levels in females in both athletes and non-athletes were higher than males to significant extent and the leptin levels of both female and male athletes were significantly lower than non-athletes. As a result, it can be said that exercise training status and gender do not affect the levels of irisin and insulin hormones, but they increased the leptin level.Öğe Effects of CoQ10 supplementation and swimming training on exhaustive exercise-induced oxidative stress in rat heart(COMENIUS UNIV, 2012) Okudan, N.; Revan, S.; Balci, S. S.; Belviranli, M.; Pepe, H.; Gokbel, H.This study examined the combined effects of swimming training and coenzyme Q(10) (CoQ(10)) supplementation on exhaustive exercise-induced oxidative stress in rat heart. The study was carried out with 4-month-old young adult male Wistar rats. Sixty four rats were divided mainly into two groups: trained and control. Each group was further divided into four subgroups: rest, exhausted, rest with CoQ(10), exhausted with CoQ(10). The training program consisted of swimming one hour each day, five days a week, for six weeks. At the end of sixth week, rats in exhausted exercise group were forced to swim until exhaustion and then they were immediately sacrificed, while rats in rest group were sacrificed at rest. Training alone or in combination with CoQ(10) supplementation reduced to increasing MDA levels due to exhaustive exercise in rat heart (p<0.05). The trained-rest with CoQ(10) group showed lower 8-OHdG levels than the control-rest with CoQ(10) group. Exhaustive exercise effect was significant on SOD activity. Exhaustive exercise increased GSH levels in control groups while decreased GSH levels in training groups (p<0.05). In conclusion, the results suggest that CoQ(10) supplementation combined with training may inhibit lipid peroxidation and DNA damage in the heart tissue. Also, it can be said that SOD activity and GSH levels were not influenced by CoQ(10) supplementation (Fig. 4, Tab. 1, Ref. 69). Full Text in PDF www.elis.sk.Öğe Gender differences in oxidative stress and antioxidant response to acute exhaustive exercise(EDIZIONI MINERVA MEDICA, 2013) Balci, S. S.Aim. The purpose of this study was to examine sex differences in changes in lipid and protein oxidation and antioxidant in plasma due to acute exhaustive exercise in young people. Methods. Forty-eight young men (21.7 +/- 0.5 years old, n = 24) and women (21.2 +/- 0.5 years old, n = 24) participated voluntarily in this study. Venous blood was collected immediately before, immediately after, and thirty minutes after acute exhaustive exercise in order to measure the plasma levels of thiobarbituric acid reactive substances (TBARS), protein carbonyl (PC), creatine kinase (CK), total antioxidant capacity (TAC), glutathione (GSH), and superoxide dismutase (SOD). Results. The effect of acute exhaustive exercise on levels of TBARS, PC, CK, TAC, GSH and activity of SOD was significant (P< 0.05). After exhaustive exercise TBARS levels significantly decreased and, PC and CK levels increased. However, the changes in levels of TBARS, PC, CK and TAC during and after exhaustive exercise were similar in men and women (P> 0.05). On the other hand, the changes in SOD activity and GSH level after exhaustive exercise were different in sex groups (P< 0.05). The SOD activity and GSH level significantly increased after exercise in women (P< 0.05) and did not significantly change in men. Conclusion. The results suggest that sex differences should be considered when evaluating the effects of acute exercise on oxidative stress.
