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Öğe Effect of acute swimming exercise on lactate levels and its relation with zinc in pinealectomized rats(JOHN WILEY & SONS LTD, 2007) Baltaci, Abdulkerim Kasim; Cumraligil, Burhan; Kilic, Mehmet; Kaya, OktayIt is argued that melatonin secreted from the pineal gland regulates the levels of zinc, which is an important trace element. Decreases in zinc levels of pinealectomized rats supports this relationship. There is an increasing amount of evidence suggesting that the pineal gland can have important effects on physical activity. The objective of the present study was to explore the changes in serum lactate levels in pinealectornized rats subjected to acute swimming exercise and its relation with zinc. Forty adult male rats of Spraque Dawley strain were equally allocated to four groups. Group 1: General Control Group. Group 2: Pinealectomized Control Group. Group 3: Swimming Control Group. Group 4: Pinealectomized Swimming Group. Serum zinc, melatonin and lactate levels were determined in the blood samples collected from the animals by a decapitation method. Zinc and melatonin levels were higher in Group I than in Groups 2, 3 and 4 (p < 0.01), higher in Group 3 than in Groups 2 and 4 (p < 0.01) and higher in Group 2 than in Group 4 (p < 0.01). The highest lactate levels were found in Group 4 (p < 0.01). Lactate levels in Group 3 were higher than those in Groups I and 2 (p < 0.01), while the levels in Groups I and 2 did not differ. Pinealectomy results in a significant increase in lactate levels in rats subjected to an acute swimming exercise. This increase in lactate levels may be associated with the decrease observed in zinc levels after pinealectomy. Copyright (C) 2006 John Wiley & Sons, Ltd.Öğe The relation between reduced serum melatonin levels and zinc in rats with induced hypothyroidism(JOHN WILEY & SONS LTD, 2008) Belviranli, Muaz; Baltaci, Abdulkerim KasimThe objective of the study was to explore the changes in melatonin and zinc levels in rats with induced hypothyroidism. Thirty adult male rats used in the study were allocated to three groups with equal numbers. Group 1: General control group which was not subjected to any procedure. Group 2: Sham-hypothyroidism group to which was administered 10 mg kg(-1) intraperitoneal (i.p.) physiologic saline (0.09% NaCl) for 4 weeks. Group 3: Hypothyroidism group which was supplemented with intraperitoneal 10 mg kg(-1) propylthiouracil (PTU) for 4 weeks. Blood samples collected from all animals at the end of the study by decapitation were analysed for serum Total T-4 (TT4), Total T-3 (TT3) Free T-4 (FT4), Free T-3 (FT3) (ELISA) as well as for melatonin (RIA) hormones and zinc levels (atomic emission). Comparison of the study groups in terms of thyroid hormones, melatonin and zinc levels showed that TT4, TT3, FT4, FT3, melatonin and zinc levels in group 3 were lower than those in groups 1 and 2 (p < 0.01). These parameters were not different in groups 1 and 2. The results of the study demonstrate that PTU supplementation for 4 weeks results in a significant inhibition in both melatonin and zinc levels. Inhibited melatonin levels may result from the decrease in zinc levels. Copyright (C) 2006 John Wiley & Sons, Ltd.Öğe Rib fractures: Could we accelerate the healing?(EUROPEAN RESPIRATORY SOC JOURNALS LTD, 2015) Calik, Mustafa; Calik, Saniye Goknil; Aribas, Olgun Kadir; Baltaci, Abdulkerim Kasim[Abstract not Available]Öğe Zinc supplementation in rats subjected to acute swimming exercise: Its effect on testosterone levels and relation with lactate(MAGHIRA & MAAS PUBLICATIONS, 2006) Kaya, Oktay; Gokdemir, Kadir; Kilic, Mehmet; Baltaci, Abdulkerim KasimOBJECTIVE: There is fairly scarce information about the effects of zinc, an essential trace element, on performance. Studies concerned with the relation between zinc and exercise mostly concentrate on the distribution of this element in the body in response to exercise. The objective of the present study is to explore how zinc supplementation affects testosterone levels and its relation with lactate in rats subjected to acute swimming exercise. MATERIALS AND METHODS: Thirty adult male rats of Spraque-Dawley species were equally allocated to 3 groups. Group 1: Control. Group 2: Group subjected to 30-minute acute swimming exercise. Group 3: Group supplemented with intraperitoneal (i.p.) zinc (3mg/kgday) for 4 weeks and subjected to 30-minute swimming exercise. Blood samples collected from all experimental animals by decapitation method were analyzed to determine free and total testosterone and lactate levels in the plasma. RESULTS: Group 3 had the highest free and total testosterone levels, followed by Group 1 and Group 2. The highest lactate levels were found in Group 2 and the levels in Group 3 were higher than those in Group 1. CONCLUSION: Results of the study demonstrate that zinc supplementation leads to a significant increase in testosterone levels and a significant decrease in lactate levels. In conclusion, physiological doses of zinc supplementation can be useful for performance.Öğe
