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    Furazolidonun Etli?k Pi?li?çlerde Büyüme Üzeri?ne Etki?si? ve Dokularda Rezi?düleri?ni?n HPLC Sistemi? ile Tayi?ni?
    (Selçuk Üniversitesi, 1989 Ocak) Acet, Ahmet; Coşkun, Behiç; Demet, Ömer; Traş, Bünyamin; Baytok, Erol
    Three experiments were conducted to examine the effect of furazolidone on the growth performance of broiler chickens and residue level and excrection time in edible meat, liver and kidney samples. In experiment 1, 240 day-old chicks were assigned to four groups with dietary treatmens including various levels (0, 5, 15, and 45 mg/kg feed) of furazolidone. The diets were fed to 42 days old and and growth performance of the groups were determined. In experiment 2, 45 chickens, 42 days old, in 3 groups were given furazolidone 0, 100, 200 mg/kg feed for 10 days. In experiment 3, two groups chickens, each had 15 chickens, were feed furazolidone 300 and 500 mg/kg feed for 5 days as a curative dose. No benefical effects of dietary furazolidone on live weights but decreased feed intake. Two chickens/group/day were slaughtered during the 7 days after withdrawal of furazolidone to determine residue lewels. Furazolidone residues were analysed in kidney, liver and muscles by using HPLC. In experiment 1, furazolidone residues were detected during the 7 days in kidney and liver samples and 3 days in muscles. In experiment 2, the residues were disappered at day 6 in kidney and liver samples and day 4 in muscles. But in experiment 3, the drug were not excreted from the tissues even at the end of the 7 days.
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    Kloramfeni?kolün Yumurta Tavuklarında Veri?m Üzeri?ne Etki?si? ve Yumurtada Kloramfeni?kol Rezi?düleri?ni?n Aranması
    (Selçuk Üniversitesi, 1989 Ocak) Acet, Ahmet; Tuncer, Şakir D.; Coşkun, Behiç; Demet, Ömer; Traş, Bünyamin; Baytok, Erol
    This study was conducted to the effect of chloramhenicol on the egg production of the laying hens and the residue levels in the eggs. Laying hens in four groups of 30 were fed on a diet containing chloramphenicol 0 ppm (group I), 20 ppm (group II) and 40 ppm (group III) for two mounths and 400 ppm (group IV) as a therapoutic dose for 5 days. Chloramphenicol did not effect on egg yield, egg weight, feed intake, and fed efficiency ratio. The residue of the chloramphenicol in the eggs were determined by using HPLC. Residues of the chloramphenicol can be routinly quantitated by this method at 2 ppb with 80-90 % recovery. No residue of chloramphenicol in the eggs from the group II was detected. But 5-20 ppb residue were faund in the eggs from group III. Increasing level of residues (58-197) were in the eggs from group IV in the first five days. Then the levels of residues decreased and were not detected on the day 30 after withdrawal of the drug.