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    Comparison of central corneal thickness measurements in normal and keratoconic eyes using ultrasonic pachymetry and OCULUS pentacam [Normal ve keratokonuslu gölerde ultrasonik pakimetri ve OCULUS pentacam ile ölçülen santral kornea kalınlıklarının karşılaştırılması]
    (Turkish Ophthalmology Society, 2011) Büyük K.; Bozkurt B.; Kamiş Ü.; Özka?nici A.; Okudan S.
    Purpose: To compare the central corneal thickness (CCT) measurements in normal and keratoconic eyes using ultrasonic pachymetry (Ocuscan® RxP) and OCULUS Pentacam Scheimpflug camera. Material and Method: In this prospective study, CCT measurements were done in 57 keratoconic eyes and 62 healthy eyes by OCULUS Pentacam and ultrasonic pachymetry, consecutively. The measurements taken by the 2 instruments were compared with paired-samples t-test. A p value <0.05 was considered as statistically significant. The correlation between the measurements was evaluated using the Pearson test. Results: The mean CCT of keratoconic eyes was 480.18±33.6 ±m with Pentacam and 465.67±34.5 ±m with ultrasonic pachymetry, which demonstrates a statistically significant difference (t=-5.87; p585 ±m (t=-3.3; p=0.005). There was a high correlation between the CCT readings done by the two methods (r=0.95, p<0.001). Discussion: The CCT measurements obtained by Pentacam in both keratoconic and healthy eyes highly correlated with the ultrasonic measurements. However, the CCT measurements taken by Pentacam were higher compared to the ultrasonic measurements; therefore, one and the same imaging technique should be used in follow-up measurements.
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    Comparison of visual field results of humphrey matrix perimetry and standard automated perimetry with SITA strategy in glaucoma and ocular hypertension subjects [Glokom ve oküler hipertansiyon hastalarinda humphrey matriks perimetrisi ve standart otomatik perimetrinin SITA stratejisi ile elde edilen görme alani sonuçlarının karşılaştırılması]
    (Turkish Ophthalmology Society, 2011) Yilmaz P.T.; Bozkurt B.; Irkeç M.
    Purpose: To compare the results of Humphrey Matrix 30-2 full threshold test and standard automated perimetry (SAP) using the Swedish Interactive Threshold Algorithm (30-2 SITA standard strategy). Material and Method: Test duration, mean deviation (MD), pattern standard deviation (PSD), number of depressed points on pattern deviation plot (PDP) at level of p<0.05 and p<0.01 were compared using the Wilcoxon signed-rank test. The correlations between MD, PSD and the number of depressed points were analyzed using Spearman's rank correlation coefficient. Kappa (?) statistic was used to determine the strength of agreement between Matrix and SAP-SITA tests. Results: PSD was higher in Matrix perimetry and the number of depressed points at level of p<0.05 was significantly higher in SAP-SITA test. MD (r=0.48), PSD (r=0.58) and the number of points depressed on PDP at the level of <0.05 and <0.01 (r=0.48 and r=0.47, respectively) showed moderate correlations between the two tests (p<0.001). The agreement between SAP and Matrix perimetry was found to be moderate (?=0.44, p<0.001). Discussion: Visual field indices and the number of depressed points on PDP of the two perimetries demonstrated only a moderate level of correlation. Therefore, a direct comparison of the global indices or individual test points should be avoided among Matrix perimetry and SAP.
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    The effect of pharmacologic pupillary dilatation on anterior segment parameters in patients with exfoliation syndrome
    (2014) Mocan M.C.; Ustunel S.; Dikmetas O.; Bozkurt B.; Irkec M.
    Purpose: The purpose of this study was to evaluate the effect of pharmacologic pupillary dilatation on anterior chamber depth (ACD) and anterior chamber angle (ACA) in eyes with exfoliation syndrome (XFS). Methods: Thirty-six eyes of 36 patients with XFS were evaluated with slit-lamp examination, Goldmann applanation tonometry and ultrasound biomicroscopy (UBM) under standard light conditions. Primary outcome parameters were defined as the change in ACD and ACA measured before and 40 min after instillation of a single drop of either 1% cyclopentolate (Group I; n = 12), 2.5% phenylephrine (Group II; n = 12) or 1% tropicamide (Group III; n = 12). Change in intraocular pressure (IOP) during the same time interval was included as a secondary outcome measure. Results: The average predilatation ACD, ACA and IOP values in the study subjects were 2.54 ± 0.40 mm, 27.9 ± 6.3° and 14.9 ± 3.1 mmHg, respectively. There were no significant differences in the mean age (p = 0.461), the female/male ratio (p = 0.232), baseline ACD (p = 0.841), ACA (p = 0.761) or IOP (p = 0.070) within the three groups. Differences in dilation induced changes in ACD (p = 0.108), ACA (p = 0.636) and IOP (p = 0.160) between the three groups were not statistically significant. Conclusion: Pupillary dilatation with a single drop of 1.0% cyclopentolate, 2.5% phenylephrine or 1% tropicamide is not associated with shallowing of the anterior chamber or narrowing of the ACA in patients with XFS who present with open angles. © 2013 Spanish General Council of Optometry.
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    Granulomatous anterior uveitis, internal ophthalmoplegia, and retinal vasculitis during chickenpox disease in a child [Suçiçe?i geçiren bir çocukta granülomatöz ön üveit, İnternal oftalmopleji ve retinal vaskülit]
    (2013) Donbalo?lu M.; Bozkurt B.; Kerimo?lu H.; Öztürk B.T.
    Herein, we report the case of a patient who had granulomatous anterior uveitis, internal ophthalmoplegia, and retinal vasculitis during chickenpox disease. A 9-year-old girl was admitted to our clinic with blurred vision and hyperemia in the right eye. Corrected visual acuity was 20/20 in both eyes. Direct/indirect pupillary reactions were negative in the right eye and pupil was dilated. Biomicroscopic examination revealed middle-sized granulomatous keratic precipitates and a severe anterior chamber reaction. Fundus examination was normal. As there were red papules all over the body she was diagnosed as anterior uveitis secondary to chickenpox and systemic/topical acyclovir, topical steroid, antihistaminic suspension, isolation, and follow-up were recommended. On day 6, anterior chamber inflammation decreased remarkably, whereas a salt-pepper appearance was observed in the retina. On day 10, a perivascular sheathing was observed, which regressed after 1 month, and her medications were slowly tapered and discontinued. Although anterior uveitis is a common finding after chickenpox, the occurrence of three different involvements is very rare.
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    Optical coherence tomography findings in bietti crystalline retinopathy [Bietti Kristalin Retinopatisinde Optik Koherens Tomografi Bulgular?]
    (2011) Öztürk B.T.; Bozkurt B.; Kamíş Ü.; Oka M.
    Optical coherence tomography (OCT) findings of two patients with Bietti crystalline retinopathy were evaluated. The fundus examination of patients who admitted to our clinic with the complain of decreased visual acuity, revealed diffuse crystalline deposits and retinal pigment epithelial atrophy at the posterior pole. In OCT, high reflective foci, thickening and increased reflectance of the retinal pigment epithelium-choriocapillaris complex were observed. These cases demonstrate that OCT is an adjunctive tool for the follow-up of crystalline deposits and atrophy of the retinal pigment epithelium in Bietti crystalline retinopathy.
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    Surgical outcomes of Ex-PRESS® mini glaucoma shunt implantation [Ex-PRESS® mini glokom İmplant cerrahisi sonuçlarımız]
    (Turkiye Klinikleri, 2014) Okka M.; Bitirgen G.; Kerimoğlu H.; Bozkurt B.; Yumak Erkoça H.
    Objective: To evaluate intraocular pressure (IOP) lowering effect and safety of Ex-PRESS® mini glaucoma drainage implant (Alcon, Fort Worth, TX) for the surgical treatment of glaucoma. Material and Methods: The data of the subjects who underwent Ex-PRESS® mini glaucoma shunt (P-50) implantation surgery in 2011 and 2012 were retrospectively reviewed. IOP before and after the treatment, visual acuity, the number of medications and complications were analyzed. Success was defined as final IOP of 6-21 mmHg with or without antiglaucomatous medications. Results: Thirty two eyes of 32 patients were included in the study. The mean age of patients and mean follow-up time were 54.43±14.56 years (range 20-77 years) and 6.34±2.95 months (range 3-16 months), respectively. Mean pretreatment IOP was 30.71±4.72 mmHg, while it was 13.21±3.51 mmHg (p<0.001) at the first week, 14.46±4.08 mmHg (p<0.001) in the first month, 14.37±2.93 mmHg (p<0.001) in the third month, 13.78±2.98 mmHg (p<0.001) in the sixth month, and 14.53±2.27 mmHg (p<0.001) in the last visit. An IOP less than 21 mmHg was achieved in all eyes in the last visit. The median value of preoperative total antiglaucomatous medications was 4.0 (3.0-5.0), however topical medications were discontinued in 81.3% of patients in the last visit. There were no complications during the follow-up period except one case of early postoperative choroidal effusion. Conclusion: Ex-PRESS® mini glaucoma shunt implantation is supposed to be an effective and safe method for the surgical treatment of glaucoma. It also helped to reduce the number of antiglaucoma medications, thus improving both the quality of life of the patients and their compliance to therapy. © 2014 by Türkiye Klinikleri.
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    Transscleral diode laser cyclophotocoagulation in refractory glaucoma [Dirençli glokom olgularında transskleral diod lazer siklofotokoagülasyon]
    (Turkish Ophthalmology Society, 2013) Bitirgen G.; Okka M.; Bozkurt B.; Do?ru I.; Kerimo?lu H.; Öztürk B.T.; Kamiş U.
    Purpose: To evaluate the safety and efficacy of transscleral diode laser cyclophotocoagulation (TSDLC) in advanced glaucoma refractory to medical or surgical treatment. Material and Method: The data of subjects who were treated with TSDLC between 2009 and 2011 were retrospectively reviewed. Intraocular pressure before and after treatment, visual acuity, the number of medications and complications were analysed. Success was defined as final IOP of 6-22 mmHg with or without antiglaucomatous medications. Results: Thirty seven eyes of 37 patients were included in the study. Mean age of patients and mean follow-up time were 61.73±17.13 years (range: 19-80 years) and 8.06±5.81 months (range: 3-22 months), respectively. Mean pretreatment IOP was 38.68±8.94 mmHg and IOP was 26.46±11.34 mmHg (p <0.01) at the second week, whereas it was 24.97±10.84 mmHg (p<0.01) at the last visit. IOP of less than 22 mmHg was achieved in 40.5% of eyes at the last visit. Mean treatment number per eye was 1.48±0.73, and more than one treatment was required in 13 (35.1%) eyes. Preoperative and postoperative mean total antiglaucomatous medications were 3.14±1.18 and 2.76±1.23, respectively. No phthisis bulbi or persistent hypotonia developed during the follow-up period. Discussion: TSDLC is an effective and safe method for the treatment of refractory glaucoma. It also served to reduce the number of antiglaucoma medications, thus improving both the quality of life of the patients and their compliance to therapy. © Galenos Yayinevi.