Yazar "Colakoglu, Fatma" seçeneğine göre listele

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    COMPARATIVE HISTOMETRICAL STUDY OF THE CEREBELLUM AND THE DETERMINATION OF SOME AgNOR PARAMETERS IN DIFFERENT AVIAN SPECIES
    (NATL VETERINARY RESEARCH INST, 2011) Sur, Emrah; Oznurlu, Yasemin; Ozaydin, Tugba; Colakoglu, Fatma; Unsal, Sadettin; Yener, Yesim
    The study was carried out to determine some characteristics of silver stained nucleolus organising regions (AgNOR parameters) of the Purkinje cells and structural differences of the cortex, if any, in the cerebellum of turkeys, ducks, pigeons, and starlings. The thickness of the molecular and granular layer at the summit of the folia was the highest in pigeons, whereas the highest value of the molecular and granular layer was determined at the deep of the folia in turkeys. The highest number of Purkinje cells per unit scale was observed in pigeons and starlings. The mean sizes of the Purkinje cells were greater in turkeys than in other species. The mean area of the Purkinje cell nucleus, AgNOR area and AgNOR counts were found to be higher in turkeys. However, there was no difference in the mean ratio of AgNOR area to Purkinje cell nucleous area among the species. In conclusion, it seems that the results obtained from this study could be of particular interest to comparative biologists and physiologists.
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    Determination of anae and acp-ase positive lymphocytes of peripheral blood and endometrium tissues in experimental hypothyroidism-ınduced rats
    (KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2019) Colakoglu, Fatma; Donmez, Hasan Huseyin
    This study was aimed to provide information about the status of the immune system by revealing changes in peripheral blood leukocyte (PBL) percentages, ANAE- and ACP-ase(+) lymphocyte rates in peripheral blood (PB) and endometrium tissues of experimental hypothyroidism-induced rats. In this study, 15 healthy female Wistar Albino rats were used. Rats were fed through 4 weeks. The Group E (experimental, n=9) is group that were made hypothyroidism by intraperitoneal methimazole enjection for 2 weeks. Rats of the Group C (control, n=6) were untreated. In the 2nd and 4th weeks, ANAE- and ACP-ase(+) lymphocyte rates of the Group E were higher than Group C in PB. Excepting eosinophil and basophil leukocyte rates, there was no statistical difference in the other PBL percentages in the both of weeks. In PB, while lymphocyte rate of the 4th week was no statistically different (P>0.05), it was found lower in Group C. There was no alteration in ANAE- and ACP-ase(+) lymphocyte rates of uterine tissue. As a result, whereas hypothyroidism caused significant alterations in PBL and T lymphocyte rates, the any marked changes was not observed in the uterine tissue.
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    Effects of aflatoxin on AgNOR activity of cells in different regions of kidney, and protective effectiveness of esterified glucomannan in ram
    (KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2013) Colakoglu, Fatma; Donmez, Hasan Huseyin
    In this study, the effects of total aflatoxin (AF) given orally on silver-staining nucleolus organizer regions (AgNORs) activity were studied in glomerulus and tubular epithelial cells of kidney in Merino rams. In addition, this study was conducted in order to evaluate the efficacy of an esterified glucomannan (EG) for protection against to aflatoxicosis. As materials, 1 year-old 32 Merino rams were used. Rams were fed through the 92 days. Control group (C) fed with the commercial feed. AF group fed with commercial feed added 250 mu g/day of total AF. EG group fed with commercial feed added 2 g/day of EG daily. AF+EG group fed with commercial feed added 250 mu g/day of total AF and 2 g/day of EG. At the end of the 92nd day the animals were sacrificed, and tissue samples were taken from the kidneys. Whereas ratio of nuclear area of the AgNOR area of cells in examinated regions of kidney was found decreased significantly (P<0.05) in the AF group compared to the control group, AF+EG group was found similar to control group (P>0.05). In conclusion, the adverse effects causing by aflatoxicosis on the kidney AgNOR activity could be ameliorated by adding EG to the ration.
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    Effects of Aflatoxin on Liver and Protective Effectiveness of Esterified Glucomannan in Merino Rams
    (HINDAWI LTD, 2012) Colakoglu, Fatma; Donmez, Hasan Huseyin
    The effects of total aflatoxin (AF) given orally on liver in Merino rams were studied. In addition, this study was conducted in order to evaluate the efficacy of an esterified glucomannan (EG) for protection against aflatoxicosis. One-year-old 32 Merino rams were divided into four equal groups. The control group (C) was fed with the commercial feed. The AF group was fed with commercial feed plus 250 mu g/day of total AF. The EG group was fed with commercial feed plus 2 g/day of EG. The AF + EG group was fed with commercial feed plus 250 mu g/day of total AF and 2 g/day of EG. After feeding period, tissue samples were taken from the liver in order to perform histological analyses. Vacuolar degeneration with small and large droplets and hydropic degeneration in hepatocytes were observed in the AF group. The ceroid pigmentation was observed in macrophages in groups or one by one. It was observed that the fat rate in hepatocytes was 2.6% in the C group, 35.5% in the AF group, 2.9% in the EG group, and 9.6% in the AF + EG group. In conclusion, the adverse effects caused by aflatoxicosis on the liver could be ameliorated by adding EG to the ration.
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    Stereological and histomorphological assessment of new zealand rabbit kidneys
    (KAFKAS UNIV, VETERINER FAKULTESI DERGISI, 2020) Selcuk, Muhammet Lutfi; Colakoglu, Fatma; Tipirdamaz, Saadettin
    The objectives of this study were to determine renal volume, volume ratios in New Zealand rabbits by stereological methods, reveal the histomorphological properties of tubulus proximalis, tubulus distalis, collecting tubule, Henie's loop and number of glomerulus. Besides, it is to investigate the possible differences between the functional subcomponents of the right and left kidneys and the effects of gender discrimination on them. The study was carried out on 9 males and 9 females healthy New Zealand rabbits' kidneys. After weighing kidneys, diameters and lengths were measured with a digital caliper. Total kidney volume and volume fractions of subcomponents of left and right kidneys were estimated by Cavalieri's method. The histological section was taken from the sampled kidneys and kidney structures in the unit area were counted. After all values of each component were expressed as ratios with in kidney, they were analyzed statistically to reveal differences between sexes. There was no statistical difference between the renal densities. The right dorsoventral and mediolateral diameters of the females and males were found to be greater than the left (P<0.05). No statistical difference was found in volume measurements with Archimedes' principle and Cavalieri's method (P>0.05). It was determined that the number of left collecting tubules in female rabbits was higher than males and it was statistically significant (P<0.05). Obtained data by making sexual dimorphism will contribute to the existing anatomical knowledge accumulation.