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    EFFECTS OF REPEATED BOUTS OF SUPRAMAXIMAL EXERCISE ON PLASMA ADIPONECTIN, INTERLEUKIN-6, AND TUMOR NECROSIS FACTOR-alpha LEVELS IN SEDENTARY MEN
    (LIPPINCOTT WILLIAMS & WILKINS, 2012) Gokbel, Hakkl; Okudan, Nilsel; Gul, Ibrahim; Belviranli, Muaz; Gergerlioglu, Hasan S.; Basarali, Mustafa K.
    Gokbel, H, Okudan, N, Gul, I, Belviranll, M, Gergerlioglu, HS, and Basarali, MK. Effects of repeated bouts of supramaximal exercise on plasma adiponectin, interleukin-6, and tumor necrosis factor-alpha levels in sedentary men. J Strength Cond Res 26(6): 1675-1679, 2012-The objective of the study was to determine the effects of repeated bouts of supramaximal exercise on plasma adiponectin, interleukin (IL)-6 and tumor necrosis factor (TNF)-alpha levels in sedentary men. Fourteen healthy, nonsmoking, and sedentary men aged between 18.4 and 21.4 years participated in the study. All the subjects performed 5 Wingate tests (WTs) with 75 g per kilogram body weight load with 2-minute intervals between the tests. Blood samples were collected at preexercise, immediately after, 15 and 60 minutes after the fifth WT. Serum and plasma samples were stored at -80 degrees C until the time of analysis for myoglobin, adiponectin, IL-6, and TNF-alpha. Plasma adiponectin levels decreased, whereas IL-6 levels increased postexercise compared with that preexercise. The TNF-alpha levels were not changed with supramaximal exercise. In conclusion, repeated bouts of supramaximal exercise cause an inflammatory response in exercised muscle and increase in plasma IL-6 levels and decrease in adiponectin concentrations.