Yazar "Karaibrahimoglu, Adnan" seçeneğine göre listele
Listeleniyor 1 - 4 / 4
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe The Comparison of Socio-Demographic and Clinical Variables of Inmates Using Gabapentin For Medicinal Purposes and Those Abusing The Drug(JOURNAL NEUROLOGICAL SCIENCES, 2017) Cicekci, Faruk; Yuksekkavas, Dincer; Aydin, Adem; Karaibrahimoglu, Adnan; Uca, Ali UlviObjective: To compare the socio-demographic and clinical data of inmates using gabapentin for medicinal purposes and those abusing the drug. Methods: The study included inmates of the Konya E-Type Prison who used gabapentin between June 2012 and December 2014 and were admitted to the prison polyclinic. The participants were divided into two groups; those using gabapentin due to existing symptoms without any labeled indication (Group 1), and those using the medication due to disorders with labeled indications (Group 2). Both groups were investigated in terms of drug addiction, drug abuse, and gabapentin abuse according to the Diagnostic and Statistical Manual-Text Revision (DSM IV-TR). Results: Nearly all inmates (n=21) using gabapentin with off-label indications (Group 1) reported using it due to muscle pain, neuropathic pain, sleep disorder, signs of anxiety, sweating, trembling, and nausea-vomiting, whereas those using gabapentin with labeled indications (Group 2) reported using it because of their diseases, such as diabetic neuropathy and epilepsy. Alcohol/substance abuse was found higher among the first-degree relatives of those using gabapentin with off-label indications (P < 0.001). The rates of substance dependence (n=10) and substance abuse (n=13) were significantly higher in Group 1 than in Group 2 (P < 0.001). Conclusion: The inmates who were diagnosed as having drug addiction and substance abuse according to the DSM-IV-TR used gabapentin after entering prison to prevent opioid withdrawal symptoms.Öğe Comparison of the Perioperative and Postoperative Effects of Levobupivacaine and of Levobupivacaine plus Adrenaline in Pediatric Tonsillectomy: A Double-Blind Randomized Study(HINDAWI LTD, 2017) Cicekci, Faruk; Sizer, Cigdem; Atici, Sait Selcuk; Arican, Sule; Karaibrahimoglu, Adnan; Kara, InciObjectives. We aimed to assess the effects of levobupivacaine and of levobupivacaine + adrenaline administered during pediatric tonsillectomy on the postoperative period. Methods. A total of 90 patients between the ages of five and twelve were divided randomly into two groups before tonsillectomy: levobupivacaine only (0.5%) 0.4 mg.kg(-1) or levobupivacaine (0.5%) 0.4 mg.kg(-1) + adrenaline (1 :200.000) administered by means of peritonsillar infiltration. Primary outcomes were postoperative pain scores recorded at various intervals until 24 hours postoperatively. Secondary outcomes included postoperative nausea and vomiting (PONV), time to first oral intake, time to the first administration of analgesics and total consumption of analgesics, and the amount of bleeding for all children. Results. In both groups, patients had the same postoperative pain scores and PONV rates, and equal amounts of analgesics were consumed up to 24 hours postoperatively. The two groups also had the same time until first oral intake, recovery time and time to the first analgesic request, and amount of bleeding. Conclusions. Perioperative levobupivacaine infiltration on its own is a valid alternative to the combination of levobupivacaine + adrenaline for perioperative and postoperative effectiveness in pediatric tonsillectomy.Öğe Ischemic priapism: Can eosinophil count and platelet functions be positive predictive factors in etiopathogenesis(CANADIAN UROLOGICAL ASSOCIATION, 2017) Sonmez, Mehmet Giray; Kara, Cengiz; Karaibrahimoglu, Adnan; Sonmez, Leyla Ozturk; Goger, Yunus Emre; Balasar, Mehmet; Taskapu, Hakki HakanIntroduction: We evaluated the relation between ischemic priapism (IP) and blood count parameters in IP patients. We especially wanted to examine the contribution of eosinophil count (EC), platelet count (PC), and mean platelet volume (MPV) values, which are suspected predictive parameters for vascular endothelium damage and venoocclusive pathogenesis and etiopathogenesis, particularly in IP. Methods: A total of 40 IP patients fulfilled the study criteria. Forty healthy volunteers in a similar age group were included as the control group. Complete blood count values were compared between the two groups. Intergroup comparisons were performed using the Mann-Whitney U test, and the chi-square test was used to assess the relationship between categorical variables in the patient groups. The area under the curve was calculated by receiver operating characteristic (ROC) regression analyses. Epidemiological diagnosis percentages were calculated by finding cutoff values. Results: The IP group's high MPV, PC, and EC values compared to those of the control group were detected to be statistically significant (p<0.001, p=0,03, p=0.001, respectively). No statistically significant difference was observed between the two groups for other blood count parameters. Statistically significant values for IP were measured as MPV: positive predictive value: 84%; EC: positive predictive value: 71.4%; and PC: positive predictive value: 61.4%. Conclusions: High MPV, PC, and EC values are significant positive predictive factors in IP etiopathogenesis. No proof was detected for other blood count parameters playing an active role in IP etiopathogenesis.Öğe Modified ridge regression parameters: A comparative Monte Carlo study(HACETTEPE UNIV, FAC SCI, 2014) Asar, Yasin; Karaibrahimoglu, Adnan; Genc, AsirIn multiple regression analysis, the independent variables should be uncorrelated within each other. If they are highly intercorrelated, this serious problem is called multicollinearity. There are several methods to get rid of this problem and one of the most famous one is the ridge regression. In this paper, we will propose some modified ridge parameters. We will compare our estimators with some estimators proposed earlier according to mean squared error (MSE) criterion. All results are calculated by a Monte Carlo simulation. According to simulation study, our estimators perform better than the others in most of the situations in the sense of MSE.
