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Öğe Investigation of effect of vitamin E on serum lipids(BLACKWELL PUBLISHING, 2007) Taspinar, M.; Kurban, S.; Mehmetoglu, I.[Abstract not Available]Öğe Investigation of serum nitric oxide, total antioxidant activity and oxidized LDL levels of obese subjects and healthy controls(WILEY, 2006) Yerlikaya, H. F.; Mehmetoglu, I.; Kurban, S.; Yilmaz, G.[Abstract not Available]Öğe Nitric oxide levels and eNOS gene polymorphism in patients with coronary artery disease documented by angiography(BLACKWELL PUBLISHING, 2007) Yılmaz, G.; Mehmetoğlu, I.; Kurban, S.; Acar, H.[Abstract not Available]Öğe Osteoprotegerin and RANKL levels in multiple sclerosis(BLACKWELL PUBLISHING, 2007) Kurban, S.; Akpınar, Zehra; Mehmetoglu, I.[Abstract not Available]Öğe Plasma myristic acid levels of obese and non-obese Turkish subjects(WILEY-BLACKWELL, 2011) Yerlikaya, H. F.; Mehmetoglu, I.; Kurban, S.[Abstract not Available]Öğe Pre-operative Atorvastatin Therapy to Decrease the Systemic Inflammatory Response after Coronary Artery Bypass Grafting(SAGE PUBLICATIONS LTD, 2008) Dereli, Y.; Ege, E.; Kurban, S.; Narin, C.; Sarigul, A.; Yeniterzi, M.The effect of pre-operative atorvastatin on systemic inflammatory response syndrome (SIRS), often seen after coronary artery bypass grafting (CABG) was evaluated in 40 patients undergoing elective CABG. Patients were divided into two groups: group I (pre-operative LDL cholesterol 100 mg/dl; n = 20) received 20 mg/day atorvastatin for at least 15 days pre-operatively; group II (pre-operative LDL cholesterol < 100 mg/dl; n = 20) did not receive antihyperlipidaemic agents. All patients underwent CABG with cardiopulmonary bypass. Blood samples were taken pre-operatively and 24 h post-operatively. There were no significant differences between the two groups in terms of demographic, pre-operative or operative parameters. At 24 h post-operatively, median high-sensitivity C-reactive protein and mean interleukin-6 levels were significantly lower in group I compared with group II. There were no other significant differences in postoperative parameters between the two groups, except for duration of stay in the intensive care unit, which was shorter in group I patients. In conclusion, pre-operative atorvastatin treatment in patients undergoing elective CABG decreased inflammation parameters and could be effective in preventing SIRS.Öğe The use of ankaferd might lead to wound dehiscence in midline laparotomy incision(2011) Alptekin, Hüsnü; Yılmaz, Hüseyin; Erdem, S.; Esen, H.; Kurban, S.; Şahin, MustafaBackground: Ankaferd Blood Stopper® offered as a hemostatic agent is a standardized herbal extract obtained from five different plants. The effects of ABS on laparotomy incision are unknown. This study was designed to assess potential effects on the healing of midline laparotomy in an experimental animal model. Material and Methods: Sixteen male Wistar albino rats were randomized into two groups and subjected to laparotomy. The study group subjected to laparotomy with local application of ABS to the bleeding points in the subcutaneous tissue, muscle and fascia and the control group subjected to laparotomy only. The rats were killed on postoperative day 7. Three types of assessment were performed: wound breaking strength, histopathology, and biochemical analysis. Results: Compared to the control group, rats in the ABS group displayed a lower wound breaking strength (p<0.05) and tissue hydroxyproline content (p<0.05). The use of ABS leads to a significant increase in malondealdehyde levels (p<0.05). Total histopathological score of groups were similar (p>0.05). Conclusion: Topical application of ABS to the subcutaneous tissue, muscle and fascia significantly impairs the wound healing by means of decreasing mechanical strength and tissue HPL levels.
