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Öğe Add-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report(KURE ILETISIM GRUBU A S, 2009) Zeytinci, Esra; Uguz, Faruk; Sahingoz, Mine; Sari, Serap; Kayhan, FatihAdd-on therapy with pramipexole in treatment resistant dysthymic disorder: A case report Despite a wide range of alternative antidepressant drugs, a considerable rate of patients with dysthymic disorder do not response to these treatments. Usually combined pharmacological drugs and augmentation therapies are used to manage this chronic psychiatric disorder. Pramipexole, a new dopamine agonist, is approved for Parkinson's disease and restless leg syndrome but accumulating evidence suggests the usage of the drug as an antidepressant. We present a young man with a history of dysthymic disorder for 15 years who improved after adding low dose pramipexole to the prior treatment.Öğe Birth Weight and Preterm Birth in Babies of Pregnant Women With Major Depression in Relation to Treatment With Antidepressants(LIPPINCOTT WILLIAMS & WILKINS, 2014) Sahingoz, Mine; Yuksel, Goksen; Karsidag, Cagatay; Uguz, Faruk; Sonmez, Erdem Onder; Annagur, Bilge Burcak; Annagur, AliObjective It is unclear whether antidepressant treatment has a preventive effect on negative neonatal outcomes due to major depression in pregnant women. The objective of the present study was to compare women with major depression treated with antidepressants, untreated women with major depression, and healthy women during pregnancy with respect to birth weight and preterm birth. Methods The study sample included a total of 23 women taking antidepressant medication, 36 women who were not taking antidepressant medication for major depression during pregnancy, and 30 healthy women. Major depression was diagnosed via the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. Results The study groups were similar with respect to sociodemographic characteristics. Compared with infants of healthy control subjects, infants of untreated major depressed women had significantly lower birth weight and shorter gestational age at delivery. There is no significant difference between infants of major depressed women treated with antidepressants and infants of healthy subjects for these variables. Conclusions Our results suggest that antidepressants may have beneficial effects on the risk of low birth weight and preterm birth in the infants of depressed women.Öğe Does a non-destructive earthquake cause posttraumatic stress disorder? A cross-sectional study(SPRINGER, 2013) Gokcen, Cem; Sahingoz, Mine; Annagur, Bilge BurcakThis study evaluated the prevalence and symptoms of posttraumatic stress disorder (PTSD) among adolescents who experienced non-destructive, moderate magnitude earthquake. Four hundred and fifty students (214 girls and 236 boys between the ages of 12-14) were selected from secondary schools located within Konya province in Turkey, 6 months after the earthquake. They were chosen to participate in this cross-sectional study by simple random sampling. The students were evaluated by the child posttraumatic stress reaction index. Of all the students, we found that 3.5 % had very severe, 20.8 % had severe, 28.4 % had moderate and 20 % had mild symptoms of PTSD and that 24.3 % had probable PTSD diagnoses. The most common PTSD symptoms were trauma-related fears, social avoidance, emotional detachment and the concentration difficulty. Limitations and implications for research studies are included in the discussion.Öğe The effects of maternal major depression, generalized anxiety disorder, and panic disorder on birth weight and gestational age: A comparative study(PERGAMON-ELSEVIER SCIENCE LTD, 2013) Uguz, Faruk; Sahingoz, Mine; Sonmez, Erdem Onder; Karsidag, Cagatay; Yuksel, Goksen; Annagur, Bilge Burcak; Annagur, AliObjective: The present study comparatively examined the impact of maternal major depression, generalized anxiety disorder and panic disorder on gestational age and birth weight. Methods: A total of 90 women (24 subjects with major depression, 19 subjects with panic disorder, 22 subjects with generalized anxiety disorder, and 25 healthy subjects) in the perinatal period who were admitted to three hospitals were included in the study. Psychiatric diagnoses were determined by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The birth weight and gestational age of the subjects in each groups were compared with one-way analysis of variance (ANOVA). Results: There were significant differences among the study groups for birth weight and gestational age (P < 0.001 for both variables). These parameters were significantly lower in the subjects with major depression (P = 0.021 and P = 0.015, respectively) and panic disorder (P < 0.001 for both variables) compared to healthy controls. Compared with major depression, panic disorder was associated more negatively with birth weight (P = 0.036). Conclusion: Major depression, and especially panic disorder, may negatively affect the gestational length and birth weight. (C) 2013 Elsevier Inc. All rights reserved.Öğe Investigation of People's Knowledge and Attitudes Towards Childhood Psychiatric Disorders and Specialists Who Work in This Field(GALENOS YAYINCILIK, 2013) Gokcen, Cem; Sahingoz, Mine; Savas, Haluk AsumanObjectives: This study aims to investigate the knowledge and attitudes of individuals who have elementary school-aged children towards childhood psychiatric disorders and to determine to what extent they could tell the difference between child psychiatrists and psychologists, the two different professional groups working in this field. Method: The study was conducted on individuals waiting for their children after school in central Konya. A questionnaire containing 29 questions was applied using the 'nonprobability sampling' method over 400 individuals who agreed to attend face-to-face interviews. Results: 92.3% of the participants responded to the question "Who is a child psychiatrist?" saying, "They are medical school graduates who have received specialist education and who are working towards the diagnosis and treatment of children's psychological health and disorders", while 52.5% responded to the question "Who is a psychologist?" using the same definition. The subjects considered 97.5% of childhood psychiatric disorders to be treatable. 62.3% of the respondents stated that they believed that the drugs used in treatment were addictive. The respondents gave the highest marks to the statement "I would take him/her to a child psychiatrist" to a question where Major Depression was defined, followed by the question "What would you do in such a situation?" and to a question where Attention Deficit Hyperactivity Disorder symptoms were defined, with a rating of 50.8% and 44.8%, respectively; and 64.8% of the respondents replied "most frequently" to a question where the symptoms of panic disorder were given, followed by the question "I would take him/her to a pediatrician." Conclusion: We found that individuals with elementary school-aged children mostly failed to distinguish between child psychiatrists and psychologists, with a widespread conviction that the drugs used in the treatment process would result in addiction. In psychiatric disorders other than panic disorder, the most rated response was "I would take him/her to a child psychiatrist." which indicate that the first choice of recourse is the child psychiatrists in childhood psychiatric disorders.Öğe One year follow-up of post-partum-onset depression: the role of depressive symptom severity and personality disorders(TAYLOR & FRANCIS LTD, 2009) Uguz, Faruk; Akman, Cemal; Sahingoz, Mine; Kaya, Nazmiye; Kucur, RahimObjective. Long-term follow-up and risk factors of persistent post-partum depression (PPD) are fairly unknown compared with its prevalence in the developing countries. In this study, we did a follow-up measure of PPD and examined the factors, which were associated with PPD 1-year post-partum. Method. Our sample comprised of 34 women. Depressive symptoms were assessed by the Edinburgh post-natal depression scale (EPDS) 6 weeks post-partum, and women with scores 12 on this scale was categorised as depressed. Personality disorders were determined at the same occasion by means of the Structured Clinical Interview for DSM-III-R personality disorders (SCID-II). One year post-partum EPDS was completed. Results. The rate of PPD 1-year post-partum was 32.4%, and it was unrelated to age at assessment, primiparity, number of children, employment status, economical status and educational level. Women depressed 1-year post-partum had significantly higher basal scores of EPDS and more often also a diagnosis of any axis II disorder; and specifically dependent and obsessive-compulsive personality disorders. In our sample, the predictors of 1-year post-partum PPD were having higher basal score of EPDS and the existence of a personality disorder. Conclusion. This study suggests that women with PPD, scoring high in the EPDS scale 6 weeks post-partum and having a personality disorder, run a higher risk for depression at 1-year follow-up.Öğe One year follow-up of postpartum-onset obsessive-compulsive disorder: A case series(PERGAMON-ELSEVIER SCIENCE LTD, 2008) Uguz, Faruk; Kaya, Nazmiye; Sahingoz, Mine; Cilli, Ali Savas; Akman, Cemal[Abstract not Available]Öğe Prevalence and Related Factors of Mood and Anxiety Disorders in a Clinical Sample of Postmenopausal Women(WILEY-BLACKWELL, 2011) Sahingoz, Mine; Uguz, Faruk; Gezginc, KazimPURPOSE: The purpose of the study was to investigate the prevalence and related factors of mood and anxiety disorders in postmenopausal women attending a gynecological outpatient clinic. METHODS: The study sample included 269 postmenopausal women. The Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, 4th edition was performed to determine the disorders. RESULTS: Ninety-two (34.2%) women had at least one mood or anxiety disorder. The most common specific disorder was generalized anxiety disorder (15.6%). The existence of any mood or anxiety disorder was associated with poorer economic level. CONCLUSIONS: Mood and anxiety disorders were frequently observed in postmenopausal women who were admitted to a gynecology outpatient clinic.Öğe QUALITY OF LIFE IN POSTMENOPAUSAL WOMEN: THE IMPACT OF DEPRESSIVE AND ANXIETY DISORDERS(SAGE PUBLICATIONS INC, 2011) Uguz, Faruk; Sahingoz, Mine; Gezginc, Kazim; Ayhan, Medine GiynasObjective: Psychiatric symptoms are frequently present in postmenopausal women. The present study aimed to investigate the impact of depressive and anxiety disorders on the quality of life (QoL) of postmenopausal women. Method: The study sample consisted of 342 postmenopausal women who presented to the Gynecology Outpatient Clinic. The Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition was used to determine depressive and anxiety disorders. The participants' QoL level was assessed by means of the World Health Organization QoL Assessment-Brief (WHOQOL-BREF). Results: Subjects without a diagnosis of depressive or anxiety disorder had significantly higher points in all domains of WHOQOL-BREF. According to linear regression analysis, all evaluated disorders except social phobia and specific phobia were independently associated with lower scores for at least one dimension of the QoL scale. However, major depression, dysthymic disorder, and generalized anxiety disorder predicted all domains of WHOQOL-BREF. Conclusion: Depressive and anxiety disorders, particularly major depression, dysthymic disorder, and generalized anxiety disorder, seem to be considerable factors affecting the QoL in postmenopausal women. (Int'l. J. Psychiatry in Medicine 2011;41:281-292)
