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Öğe Changes in abdominal dimensions during late gestation and early lactation in Holstein-Friesian heifers and cows and their relationship to left displaced abomasum(British Veterinary Association, 2007) Wittek T.; Sen I.; Constable P.D.The changes in abdominal dimensions and contour during late gestation and early lactation were investigated in 44 Holstein-Friesian cattle, 20 normal heifers and 17 normal cows, and seven cows that had a left displaced abomasum (LDA) surgically corrected by a right flank omentopexy in a previous lactation. Abdominal measurements were made eight times during the six months spanning the last trimester of pregnancy and the first three months of lactation, they included the circumference of the thorax and abdomen, the depth and width of the abdomen, the vertical distance between the ventral abdomen and the descending duodenum, the height at the withers, and the length of the trunk. There were significant changes in these dimensions during the last trimester of pregnancy, immediately after parturition and during the first three months of lactation. The depth of the abdomen and the vertical distance between the ventral abdomen and the descending duodenum were greater in the cows with a previous history of LDA than in those without.Öğe The levels of trace elements and macrominerals in calves with sepsis(Veteriner Fakultesi Dergisi, 2020) Coskun A.; Aydogdu U.; Guzelbektes H.; Sen I.The aim of this study was to determine the levels of macrominerals and trace elements in the blood of newborn calves with sepsis. The study was carried out on a total of 30 calves, aged 2-35 days old, of which 25 with sepsis and 5 healthy. In clinical examination, prolonged capillary refill time and tachypnea were observed in calves with sepsis. The levels of Cu, K, P and S in calves with sepsis were higher compared to the control group, and the levels of Na, total and ionized Ca, Fe and Zn were also lower compared to the control group. In conclusion, in this study, significant increase in K and Cu concentrations and significant decrease in Na and Ca concentrations were found in calves with sepsis. According to the results, K, Cu, Na and Ca may have important roles in the pathophysiology of sepsis. © 2020, Veteriner Fakultesi Dergisi. All rights reserved.Öğe Myocardial depression in a calf with septic shock(BMJ Publishing Group, 2018) Naseri A.; Turgut K.; Sen I.; Ider M.; Akar A.A 10-day-old, 32-kg Simmental heifer calf was presented with a 2-day history of diarrhoea and anorexia. The diagnosis of septic shock was based on the presence of severe sepsis and hypotension that could not be reversed with fluid resuscitation. Echocardiographic findings included a hypokinetic left ventricle with decreased left ventricle ejection fraction, stroke volume and cardiac index. The end-systolic volume index (ESVI) was elevated to 36.14 ml/m2 and a depressed end-diastolic volume index (EDVI) (51.31 ml/m2). Left ventricular depression was normalised 24 hours after resuscitation. It was concluded that myocardial depression could be reversible in the calf with septic shock; however, according to the postresuscitation echocardiographic findings, a decreased ESVI suggests vasomotor dysregulation and a decreased EDVI suggests alterations in vascular permeability. These were the major implications of sepsis and resulted in multiple organ dysfunction and death. © 2018 British Veterinary Association.Öğe Serum gastrin in dogs with acute or chronic gastritis and positive or negative for Helicobacter sp. in the stomach(2008) Guzelbektes H.; Coskun A.; Ortatatli M.; Sen I.The relationship between gastrin levels and presence of Helicobacter-like organisms (HLO) in dogs with acute or chronic gastritis was investigated. For this purpose, a total of 52 crossbred Kangal Dogs aging 2-5 years were used; including 12 dogs with acute gastritis, 25 dogs with chronic gastritis, and 15 healthy dogs. Blood samples were collected from the vena cephalica. Serum gastrin levels were measured using commercial competitive binding radioimmunoassay. HLO were found in 64%, 58.3%, and 60% of animals with chronic gastritis or acute gastritis, and controls, respectively. The gastrin levels in dogs with chronic gastritis were higher than in those with acute gastritis and controls. There were no significant differences between the gastrin levels in all groups, with regard to HLO positive versus HLO negative dogs. In conclusion, HLO incidence was generally found in high levels in all the dogs. However, HLO did not primarily affect the stomach mucosal damage. In the mean time, there was no relation between the levels of serum gastrin in dogs with gastritis, either being HLO positive or negative. The results of the study showed that higher gastrin levels in dogs with gastritis were related to severe gastric lesions and mucosal damage.