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  • Küçük Resim Yok
    Öğe
    A Randomized Comparison of Dimenhydrinate, Metoclopramide and Placebo for the Prevention of Nausea and Vomiting Following Intrathecal Fentanyl and Morphine in Cesarean Delivery
    (Nobel Ilac, 2010) Duman, Ateş; Apilioğulları, Seza; Gök, Funda; Sütçü, Erdinç; Soysal, Sema; Toy, Harun
    Objective Intrathecal morphine for cesarean section provides excellent postoperative analgesia however is associated with significant nausea and vomiting This study was designed to compare the effectiveness of prophylactic use of dimenhydrinate and metoclopramide to placebo for the prevention of nausea and vomiting following intrathecal fentanyl and morphine used for cesarean section Material and Method Two hundred ten patents undergoing cesarean section under spinal anesthesia were included in this double blind and randomized study Spinal anesthesia was performed with 10 mg of hyperbaric bupivacaine combined with 20 mu g fentanyl and 200 mu g morphine After clamping the umbilical cord patients were randomly allocated to receive 50 mg dimenhydrinate intravenously (Group D) 10 mg metoclopramide (Group M) or 0 9% NaCl as placebo (Group P) The incidence of postoperative nausea or vomiting (PONV) during the first 24 postoperative hours was evaluated Results The postoperative incidence of PONV was significantly lower in Group D (11%) than in Group M (28%) and Group P (32%) (p=0 02) The incidence and severity of postoperative nausea were significantly lower with the use of dimenhydrinate as compared to metoclopramide and placebo group (p= 0 01) Conclusion The prophylactic use of dimenhydrinate (50 mg intravenously) as compared either to metoclopramide (10 mg) or placebo effectively decreased the incidence of PONV following intrathecal fentanyl and morphine for cesarean section.
  • Küçük Resim Yok
    Öğe
    Vagina Akıntısı Örneklerinin Mycoplasma ve Nonspesifik Bakteriler Yönünden Değerlendirilmesi
    (1996) Fındık, Duygu; Güler, Leyla; Soysal, Sema
    Vagina akıntısı yakınması ile gelen 60 hastadan alınan ve pH'ı 4.5'den yüksek olan vagina akıntısı örnekleri kültürleri yapılarak değerlendirilmiştir. Direkt mikroskobide altı örnekte Trichomonas vaainalis saptanmıştır. Yapılan kültürlerde ise sekiz olguda Candida türleri, beş olguda S. aureus. sekiz olguda ise Mycoplasma hominis üremiştir. Onbeş hastanın kültüründe üreme olmamıştır.