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Öğe Antiproliferative and apoptotic effects of noscapine on MCF-7 and MDA-MB-231 human breast cancer cell lines(WILEY-BLACKWELL, 2016) Kocak, F. E.; Kocak, C.; Ozturk, B.; Tekin, G.; Vatansev, H.[Abstract not Available]Öğe Brefeldin A exerts differential effects on various phenotypes of breast cancer cell lines(WILEY-BLACKWELL, 2016) Tekin, G.; Ozturk, B.; Ozer, E. K.; Bariskaner, H.; Unlu, A.[Abstract not Available]Öğe The effect of obesity surgery on ghrelin levels(WILEY, 2017) Ayranci, M.; Vatansev, H.; Saracligil, B.; Tekin, G.; Yilmaz, H.; Vatansev, H.[Abstract not Available]Öğe Effect of static magnetic field with antiproliferative compounds on MDA MB-231 cell line(WILEY, 2017) Tekin, G.; Ozturk, B.[Abstract not Available]Öğe The effect of vitamin D on MCF-7 breast cancer cell metabolism(COMENIUS UNIV, 2017) Saraçlıgil, B.; Öztürk, B.; Ünlü, Ali; Abuşoğlu, Sedat; Tekin, G.The role of vitamin D in calcium absorption and bone health is known. The studies revealed that vitamin D modulates breast cancer cell growth and it is also associated with a reduced breast cancer risk. The primary objective of this study was to highlight the metabolic effect of Vitamin D on MCF-7 breast cancer cell line. For that purpose, we checked the apoptosis, energy, amino-acid and acylcarnitine levels in cancer cells, that the study propose, that la, 25(OH)(2)D-3 could inhibit cell growth in a dose and time dependent manner. IC50 dose was calculated as 145 nM for vitamin D. We observed the apoptosis level in vitamin D groups, which were 18, 28 and 38.5 % at 24, 48 and 72 hours, respectively. During metabolic screening analysis, it was observed that glutamine, methionine and glutamic acid levels were treated more by Vitamin D groups in cell line and also, that acylcarnitine level was increased in 24 and 48 hour groups when compared to the control, but decreased in 72 hours. Further studies are needed to analyze the role of amino acids and acylcarnitines for early apoptosis and cancer metabolism (Tab. 2, Fig. 4, Ref. 24). Text in PDF www.elis.sk.Öğe Effects of Exercise on ADAMTS-4 and ADAMTS-5 Levels in Sport Horses(WILEY, 2017) Kandir, S.; Tekin, G.; Er, C.; Karakurt, S.[Abstract not Available]Öğe Öğe NEGATIVE CORRELATION OF RHO-MIR-15-5P AND MAP3K IN HYPERTENSIVE RAT MODELS(LIPPINCOTT WILLIAMS & WILKINS, 2017) Tekin, G.; Gul, A.; Karakurt, S.[Abstract not Available]Öğe Sera levels of homoarginine, homocysteine and ischemia modified albumin in patients with breast cancer(WILEY, 2019) Kosova, F.; Abuşoğlu, Sedat; Beksaç, Ö. K.; Tekin, G.; Çetin, B.; Dinçel, A. Sepici.; Arı, Z.; Ünlü, Ali[Abstract not Available]
