Effect of Iron Supplementation on Oxidative Stress and Antioxidant Status in Iron-Deficiency Anemia

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dc.contributor.authorKurtoğlu, Erdal
dc.contributor.authorUğur, Ayşegül
dc.contributor.authorBaltacı, Abdulkerim Kasım
dc.contributor.authorÜndar, Levent
dc.date.accessioned2020-03-26T16:45:36Z
dc.date.available2020-03-26T16:45:36Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was designed to measure the effect of iron supplementation on antioxidant status in iron-deficient anemia, including the time for hemoglobin normalization and at the time of filling of iron body stores. The extent of plasma lipid peroxidation was evaluated by measuring the levels of malondialdehyde and glutathione peroxidase (GSH-Px), and the activities of superoxide dismutase (SOD) and catalase in 63 patients with iron-deficiency anemia before and after 6 wk of iron supplementation and at the time when body iron stores are saturated. After 6 wk of iron supplementation, a significant decrease of oxidative stress was observed in the treated subjects relative to controls (p<0.05). No significant differences existed between treated patients at 6 wk and at the end of the study. The erythrocyte levels of catalase, SOD, and GSH-Px were significantly lower in treated patients relative to controls (p<0.05). These levels increased after 6 wk of supplementation (p<0.05) and showed no significant differences with those at the end of the study.en_US
dc.identifier.citationKurtoğlu, E., Uğur, A., Baltacı, A. K., Ündar, L., (2003). Effect of Iron Supplementation on Oxidative Stress and Antioxidant Status in Iron-Deficiency Anemia. Biological Trace Element Research, (96), 117-123. Doi: 10.1385/BTER:96:1-3:117
dc.identifier.doi10.1385/BTER:96:1-3:117en_US
dc.identifier.endpage123en_US
dc.identifier.issn0163-4984en_US
dc.identifier.pmid14716090en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage117en_US
dc.identifier.urihttps://dx.doi.org/10.1385/BTER:96:1-3:117
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18428
dc.identifier.volume96en_US
dc.identifier.wosWOS:000187916600009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofBiological Trace Element Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectİron-Deficiency Anemiaen_US
dc.subjectİron Replacementen_US
dc.subjectOxidative Stressen_US
dc.subjectAntioxidantsen_US
dc.titleEffect of Iron Supplementation on Oxidative Stress and Antioxidant Status in Iron-Deficiency Anemiaen_US
dc.typeArticleen_US

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