Oxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: the effect of coenzyme Q10

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dc.contributor.authorGul, I.
dc.contributor.authorGokbel, H.
dc.contributor.authorBelviranli, M.
dc.contributor.authorOkudan, N.
dc.contributor.authorBuyukbas, S.
dc.contributor.authorBasarali, K.
dc.date.accessioned2020-03-26T18:15:33Z
dc.date.available2020-03-26T18:15:33Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim. The purpose was to determine the changes of oxidative stress and antioxidant markers in plasma after repeated bouts of supramaximal exercise and the effects of coenzyme Q10 supplementation on these changes. Methods. This randomized, double blind, crossover study was composed of two 8-week periods of supplementation with either 100 mg.day(-1) CoQ10 or placebo. Fifteen healthy and sedentary men participated in the study. Five Wingate tests with 2 min rest between tests were performed. Blood samples were collected at rest, immediately after, 15 and 60 min after the fifth Wingate test for oxidative stress (malondialdehyde, nitric oxide, xanthine oxidase and adenosine deaminase) and antioxidant (superoxide dismutase, glutathione peroxidase and uric acid) markers. Results. At baseline exercise session, malondialdehyde increased 15 and 60 min after the exercise compared to the rest and immediately after the exercise. Malondialdehyde at rest, immediately after and 60 min after the exercise decreased with coenzyme Q10 supplementation when compared to baseline. At baseline exercise session, uric acid increased 15 and 60 min after the exercise when compared to the rest. In conclusion, lipid peroxidation and antioxidant defense increase after repeated short-term supramaximal exercise. Conclusion. Coenzyme Q10 supplementation partially prevents the increase in lipid peroxidation after repeated short-term supramaximal exercise.en_US
dc.description.sponsorshipSelcuk UniversitySelcuk University [SABE 06202030]en_US
dc.description.sponsorshipScientific Research and Project Coordinator of Selcuk University supported this study (Fund number: SABE 06202030).en_US
dc.identifier.endpage312en_US
dc.identifier.issn0022-4707en_US
dc.identifier.issue2en_US
dc.identifier.pmid21681167en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage305en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26704
dc.identifier.volume51en_US
dc.identifier.wosWOS:000294593100018en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEDIZIONI MINERVA MEDICAen_US
dc.relation.ispartofJOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCoenzyme Q10en_US
dc.subjectExerciseen_US
dc.subjectOxidative stressen_US
dc.subjectAntioxidantsen_US
dc.titleOxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: the effect of coenzyme Q10en_US
dc.typeArticleen_US

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