Does the Myocardial Performance Index Affect Pulmonary Artery Pressure in Patients With Mitral Stenosis? A Tissue Doppler Imaging Study

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dc.contributor.authorÖzdemir, Kurtuluş
dc.contributor.authorAltunkeser, Bülent Behlül
dc.contributor.authorGök, Hasan
dc.contributor.authorİçli, Abdullah
dc.date.accessioned2020-03-26T16:45:34Z
dc.date.available2020-03-26T16:45:34Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: The relation between systolic pulmonary artery pressure (PAP) and mitral stenosis (MS) has been poorly understood. Although the mitral valve area (WA) is an important factor affecting the PAP, there is a wide spectrum of the PAP in patients with MS despite a similar WA. So, we analyzed whether the left and right ventricular myocardial performance index (MPI) correlated with the PAP. Methods: Two-dimensional Doppler echocardiography was performed in 46 patients with MS. The left atrial diameter, mean mitral gradient, and WA were measured. The PAP was derived from the tricuspid regurgitant jet velocity. The ejection time (ET), isovolumetric relaxation time (IRT), and contraction time (ICT) were measured on annulus of interventricular septum, lateral, inferior and anterior wall of left ventricle, and right ventricle free wall from apical two- and four-chamber views in patients with MS and 40 age-matched healthy patients by tissue Doppler imaging (TDI). Then the MPI was calculated as (IRT + ICT)/ET for both left and right ventricle. The correlation of PAP with WA, mean mitral gradient, left atrial diameter, and left and right ventricular MPI was evaluated. Results: WA and PAP were measured as 1.57 +/- 0.39 cm(2) (0.8-2.5 cm(2)) and 42 +/- 16 mmHg, respectively. It was determined that the MPI increased inpatients with MS (0.59 +/- 0.1 vs 0.48 +/- 0.07, P < 0.001). It was also demonstrated that the WA, left atrial diameter, mean diastolic gradient, and left ventricular MPI were correlated with PAP (r = -0.39 (P = 0.0071, r = 0.43 (P = 0.0031,.r = 0.58 [P < 0.001), and r = 0.65 [P < 0.001), respectively). In multivariate analysis, although the PAP correlated with mean diastolic gradient and MPI (r = 0.39 (P = 0.013), and r = 0.48 [P < 0.001)), it did not correlate with left atrial diameter and MVA. The PAP also correlated with right ventricular MPI (r = 0.63 (P < 0.001)). Conclusion: This study demonstrates that the left ventricular MPI obtained by TDI is an important marker of PAP, and right ventricular MPI correlates with the PAP in patients with MS.en_US
dc.identifier.citationÖzdemir, K., Altunkeser, B. B., Gök, H., Çli, A., (2003). Does the Myocardial Performance Index Affect Pulmonary Artery Pressure in Patients With Mitral Stenosis? A Tissue Doppler Imaging Study. Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques, 20(3), 249-256. DOİ: 10.1046/j.1540-8175.2003.03022.x
dc.identifier.doi10.1046/j.1540-8175.2003.03022.xen_US
dc.identifier.endpage256en_US
dc.identifier.issn0742-2822en_US
dc.identifier.issn1540-8175en_US
dc.identifier.issue3en_US
dc.identifier.pmid12848662en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage249en_US
dc.identifier.urihttps://dx.doi.org/10.1046/j.1540-8175.2003.03022.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18418
dc.identifier.volume20en_US
dc.identifier.wosWOS:000182462100006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorÖzdemir, Kurtuluş
dc.institutionauthorAltunkeser, B. Bülent
dc.institutionauthorGök, Hasan
dc.institutionauthorÇ, Abdullah
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofEchocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMitral stenosisen_US
dc.subjectMyocardial performance indexen_US
dc.subjectPulmonary artery pressureen_US
dc.titleDoes the Myocardial Performance Index Affect Pulmonary Artery Pressure in Patients With Mitral Stenosis? A Tissue Doppler Imaging Studyen_US
dc.typeArticleen_US

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