Effect of caudal block on stress responses in children

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dc.contributor.authorTuncer, S
dc.contributor.authorYosunkaya, A
dc.contributor.authorReisli, R
dc.contributor.authorTavlan, A
dc.contributor.authorCicekci, F
dc.contributor.authorOtelcioglu, S
dc.date.accessioned2020-03-26T16:48:14Z
dc.date.available2020-03-26T16:48:14Z
dc.date.issued2004
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractBackground: The present study was performed during lower abdominal and genitourinary surgery, to assess the effects of caudal block on plasma cortisol, prolactin, insulin and glucose concentrations during and after surgery. Methods: Thirty male children aged 3-10 years who were scheduled for elective surgery, were selected for the study. The children were premedicated with oral midazolam 0.5 mg/kg. All children received induction with nitrous oxide in oxygen and sevoflurane. The children were randomly allocated into two groups: Group I, control group (n=15) and group II, caudal group (n=15). Anesthesia was maintained by face mask with the same agent in both groups. Caudal block was performed with 0.25% bupivacaine 2 mg/kg after induction of anesthesia in the caudal group. Blood samples were obtained after induction of anesthesia (T-0) in order to measure baseline concentrations of cortisol, prolactin, glucose and insulin. Additional samples were obtained 30 min after the start of surgery (T-1), and 60 min after the end of surgery (T-2). Results: All of the basal values (T-0) were within the normal ranges accepted by Meram Medical Faculty of Selcuk University for children of this age group and there were no differences between the groups (P>0.05). In both groups, glucose concentration increased at T-1, compared with T-0 and T-2 values (P<0.05). However glucose concentration was lower in the caudal group than in the control group at T-1 (P<0.05). In both groups, prolactin concentration increased at T-1, compared with T-0 (P<0.05). The mean plasma prolactin and cortisol concentration were lower in the caudal group than the control group at T-1 and T-2 (P<0.05). The mean insulin concentration was lower in the caudal group than the control group at T-2 (P<0.05). Conclusion: These results indicate that caudal anesthesia suppresses the metabolic and endocrine responses to stress associated with lower abdominal and genitourinary surgery in children.en_US
dc.identifier.doi10.1111/j.1328-0867.2004.01839.xen_US
dc.identifier.endpage57en_US
dc.identifier.issn1328-8067en_US
dc.identifier.issue1en_US
dc.identifier.pmid15043665en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1328-0867.2004.01839.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19004
dc.identifier.volume46en_US
dc.identifier.wosWOS:000188670500011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHING ASIAen_US
dc.relation.ispartofPEDIATRICS INTERNATIONALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectcaudal blocken_US
dc.subjectcortisolen_US
dc.subjectglucoseen_US
dc.subjectinsulinen_US
dc.subjectprolactinen_US
dc.subjectstress responseen_US
dc.titleEffect of caudal block on stress responses in childrenen_US
dc.typeArticleen_US

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