The relationship between Polycystic ovary syndrome and vitamin D levels

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dc.contributor.authorYılmaz, Setenay Arzu
dc.contributor.authorAltınkaya, Sündüz Özlem
dc.contributor.authorKebabcılar, Ayşe Gül
dc.contributor.authorKerimoğlu, Özlem Seçilmiş
dc.contributor.authorPekin, Aybike Tazegül
dc.contributor.authorAbuşoğlu, Sedat
dc.contributor.authorÇelik, Çetin
dc.date.accessioned2020-03-26T19:07:38Z
dc.date.available2020-03-26T19:07:38Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: The main aim of this study was to determine the association of serum 25-hydroxyvitamin D (25-OH D) levels with hormonal, clinical and metabolic profile in patients with and without Polycystic ovary syndrome (PCOS). Materials and Methods: Forty-eight normal-weight (body mass index (BMI) of 19-24.99 kg/m(2)) women with PCOS, 36 overweight (BMI of 25-29.9 kg/m(2)) women with PCOS and 56 normal-weight controls participated in the study. Blood samples were collected in the early follicular phase (between day 2 and day 5 of the menstrual cycle) at 9: 00 am after an overnight fast. Circulating concentrations of 25-OH D, luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, TSH, free testosterone, dehydroepiandrosterone sulphate (DHEA-SO4), 17-hydroxyprogesterone, sex hormone-binding globulin (SHBG), fasting insulin, fasting glucose, and lipid profile were assessed. Results: Normal weight (BMI 19-24.99 kg/m(2)) and overweight (BMI 25-29.99 kg/m(2)) women with PCOS were compared with normal-weight controls and lower 25-OH D levels were found in both PCOS groups (p<0.05 and p<0.01, respectively 25-OH D significantly negatively correlated with waist circumference (WC), waist-to-hip ratio (WHR), free testosterone and modified Ferriman-Gallwey scores, however, there was a positive correlation between 25-OH D and SHBG levels (p<0.05). Conclusion: Our findings suggest that PCOS is associated with hypovitaminosisen_US
dc.identifier.doi10.4274/tjod.76148en_US
dc.identifier.endpage24en_US
dc.identifier.issn2149-9322en_US
dc.identifier.issn2149-9330en_US
dc.identifier.issue1en_US
dc.identifier.pmid28913035en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage18en_US
dc.identifier.urihttps://dx.doi.org/10.4274/tjod.76148
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32680
dc.identifier.volume12en_US
dc.identifier.wosWOS:000422572900006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofTURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectVitamin Den_US
dc.subjectPolycystic ovary syndromeen_US
dc.subjectinsulin resistanceen_US
dc.titleThe relationship between Polycystic ovary syndrome and vitamin D levelsen_US
dc.typeArticleen_US

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