Nutraceutical potential of Corylus avellana daily supplements for obesity and related dysmetabolism

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dc.contributor.authorMollica, Adriano
dc.contributor.authorZengin, Gökhan
dc.contributor.authorStefanucci, Azzurra
dc.contributor.authorFerrante, Claudio
dc.contributor.authorMenghini, Luigi
dc.contributor.authorOrlando, Giustino
dc.contributor.authorBrunetti, Luigi
dc.date.accessioned2020-03-26T19:54:52Z
dc.date.available2020-03-26T19:54:52Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractIn this study, the nutraceutical potential of two hazelnut varieties (Turkey and Italy) were examined by studying several aspects including the phytochemical properties, antioxidant potential, cell viability and ex vivo neuroprotective potential. Results showed that the Turkish hazelnut had the higher concentration of phenolic acids, flavonoids, higher antioxidant capacity and enzyme inhibition properties and lower saturated fatty acid concentration than the Italian sample. The in vivo studies showed that compared to the Italian hazelnuts, the addition of Turkish hazelnuts to high fat diet was associated with a more significant decrease in body weight, food consumption, atherogenic index, lipid peroxidation levels and biochemical/morphological markers of liver injury. Also, from our results, the two hazelnut varieties were protective against beta-amyloid-induced neurochemical changes and high-fat diet induced alteration of metabolic indices.en_US
dc.description.sponsorshipItalian Health MinistryMinistry of Health, Italy [880]en_US
dc.description.sponsorshipThe Ex vivo Studies, have been conducted on prostate specimens obtained as residual material from vehicle-treated rats randomized in our previous experiments approved by Local Ethical Committee (University "G. d'Annunzio" of Chieti-Pescara) and Italian Health Ministry (Project N. 880 definitely approved by Italian Health Ministry on 24th August 2015).en_US
dc.identifier.doi10.1016/j.jff.2018.06.016en_US
dc.identifier.endpage574en_US
dc.identifier.issn1756-4646en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage562en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jff.2018.06.016
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36812
dc.identifier.volume47en_US
dc.identifier.wosWOS:000439019200059en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofJOURNAL OF FUNCTIONAL FOODSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectbeta-amyloiden_US
dc.subjectDieten_US
dc.subjectFaten_US
dc.subjectHazelnuten_US
dc.subjectFunctional fooden_US
dc.subjectNutraceuticalen_US
dc.titleNutraceutical potential of Corylus avellana daily supplements for obesity and related dysmetabolismen_US
dc.typeArticleen_US

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