Seasonal variation of the onset of presentations in stage 1 sarcoidosis

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dc.contributor.authorDemirkök, Sevtap Sipahi
dc.contributor.authorBaşaranoğlu, Metin
dc.contributor.authorAkbilgiç, Oğuz
dc.date.accessioned2020-03-26T17:04:16Z
dc.date.available2020-03-26T17:04:16Z
dc.date.issued2006
dc.departmentSelçuk Üniversitesien_US
dc.description15th Annual Congress of the European-Respiratory-Society -- SEP 17-21, 2005 -- Copenhagen, DENMARKen_US
dc.description.abstractSarcoidosis is a chronic disease with an unknown aetiology. Our aim was to evaluate the pattern of seasonality of stage 1 sarcoidosis subjects who had symptoms by all cases, by age and by both genders. In this study, we used Roger's test for cyclic variation to prove that this seasonal variation was more than chance. Four hundred ninety-two consecutive patients with sarcoidosis who presented different clinical symptoms were included in this retrospective cohort study. According to the chest X-ray examinations, 185 patients had stage 1, while 307 patients in control group had stage 0, 2, 3 and 4 sarcoidosis. The demographic features, presenting clinical features, course of the disease, initial diagnostic methods and both the month and the age at the initial diagnosis for each patient were analysed on chart reviews. Roger's test for cyclic variation was used to determine the significance of any seasonal variation of incidence. Otherwise, t-test was used. The distribution of cumulative monthly presentations for patients with stage 1 peaked in April (108% above the average) and was lowest in October, November and December (48% below the average) (p < 0.001). Seasonality of the control group peaked in May (84% above the average) and was lowest in August (69% below the average) (p < 0.001). The seasonal pattern of subjects within both groups was influenced by some age groups and by both genders (p < 0.05). Some differences in the amplitude of the seasonal variation by age and by both genders increase the possibility of interactions among age, gender and the disease. Further well-designed and prospective studies are required to better understand the importance of our findings and the pathogenesis of the disease.en_US
dc.description.sponsorshipEuropean Resp Socen_US
dc.identifier.doi10.1111/j.1742-1241.2005.00773.xen_US
dc.identifier.endpage1450en_US
dc.identifier.issn1368-5031en_US
dc.identifier.issn1742-1241en_US
dc.identifier.issue11en_US
dc.identifier.pmid17073840en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1443en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1742-1241.2005.00773.x
dc.identifier.urihttps://hdl.handle.net/20.500.12395/20665
dc.identifier.volume60en_US
dc.identifier.wosWOS:000241190700021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWILEYen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectsarcoidosisen_US
dc.subjectseasonalityen_US
dc.subjectstage 1en_US
dc.subjectageen_US
dc.subjectgenderen_US
dc.titleSeasonal variation of the onset of presentations in stage 1 sarcoidosisen_US
dc.typeArticleen_US

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