A biochemical and histochemical study on the activity of acid peptide hydrolase in the hypothalamus at some periods of starvation and refeeding after starvation

dc.contributor.authorTemur A.
dc.contributor.authorKarada? H.
dc.contributor.authorAskerov F.
dc.contributor.authorDönmez H.H.
dc.date.accessioned2020-03-26T16:58:39Z
dc.date.available2020-03-26T16:58:39Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was carried out to determine acid peptide hydrolyse activity in the homogenate of the lateral (feeding centre) and ventro-medial (satiety centre) nuclei of hypothalamus and fractions of the cells (mitochondria, nucleus, cystocoele) in those centres of rats fed after being starved for a five day period. One hundred and sixty Wistar Albino rats were used in this study. The rats were starved for periods of 1, 3, 5 and 7 d. The rats starved for 5 d were then allowed to eat for periods of 5, 15 and 30 d. The activity of acid peptide hydrolyse was biochemically determined in the feeding and satiety centres. In addition, histochemical study was also done in these centres. It was observed that the activity of acid peptide hydrolyse became closer to the levels of the control group in the satiety centre on the 30th d of access to food after a 5 d starvation. It was concluded that the feeding centre was more sensitive to starvation than the satiety centre and the satiety centre was restored faster than the feeding centre.en_US
dc.identifier.endpage2486en_US
dc.identifier.issn0970-7077en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage2479en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19994
dc.identifier.volume17en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofAsian Journal of Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAcid peptide hydrolyseen_US
dc.subjectHypothalamusen_US
dc.subjectStarvationen_US
dc.titleA biochemical and histochemical study on the activity of acid peptide hydrolase in the hypothalamus at some periods of starvation and refeeding after starvationen_US
dc.typeArticleen_US

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