Applications of Metabolomics in Reproductive Biology

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dc.contributor.authorCazaux Velho A.L.
dc.contributor.authorOliveira R.
dc.contributor.authorDinh T.
dc.contributor.authorMoura A.
dc.contributor.authorKaya A.
dc.contributor.authorMemili E.
dc.date.accessioned2020-03-26T19:43:42Z
dc.date.available2020-03-26T19:43:42Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractMetabolomics can be performed associated with other omics approaches such as genomics, transcriptomics, and proteomics. For example, a recent study showed interesting results using an Integrative Personal Omics Profile (iPOP) to identify markers for possible diseases affecting an individual. This chapter suggests that such a method leads to an early diagnosis and facilitates prevention of certain diseases, such as type 2 diabetes, aplastic anemia, human rhinovirus infection, and respiratory syncytial virus infection. For assisted reproductive technologies (ART), metabolomics methods have been chosen as noninvasive approaches to improve the assessment of embryo quality. Metabolic profiling analysis of follicular fluids (FF) from lactating cows and heifers by gas chromatography-mass spectrometry (GC-MS) identified the presence of greater concentrations of saturated fatty acids in follicles from cows than those from heifers. Large animals have been used as models for research of human disease and physiology due to their specific physiological characteristics, sometimes similar to the human. © 2017 by John Wiley & Sons, Inc. All rights reserved.en_US
dc.identifier.doi10.1002/9781118881286.ch20en_US
dc.identifier.endpage518en_US
dc.identifier.isbn9781118881286; 9781118881606
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage509en_US
dc.identifier.urihttps://dx.doi.org/10.1002/9781118881286.ch20
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35738
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherwileyen_US
dc.relation.ispartofAnimal Models and Human Reproductionen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAssisted reproductive technologiesen_US
dc.subjectFollicular fluidsen_US
dc.subjectGas chromatography-mass spectrometryen_US
dc.subjectHuman diseaseen_US
dc.subjectHuman rhinovirus infectionen_US
dc.subjectIntegrative Personal Omics Profileen_US
dc.subjectMetabolomicsen_US
dc.subjectReproductive biologyen_US
dc.subjectRespiratory syncytial virus infectionen_US
dc.titleApplications of Metabolomics in Reproductive Biologyen_US
dc.typeBook Chapteren_US

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