Plasma Homocysteine Concentrations in Adolescents With Subclinical Hypothyroidism

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dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorPirgon, Özgür
dc.contributor.authorErkul, İbrahim
dc.date.accessioned2020-03-26T16:45:57Z
dc.date.available2020-03-26T16:45:57Z
dc.date.issued2003
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: Hyperhomocysteinemia is a risk factor for premature atherosclerotic vascular disease and venous thrombosis. The aim of the present study was to assess plasma total homocysteine (tHCys) concentrations in adolescent patients with subclinical hypothyroidism. Patients and Methods: Nineteen patients with subclinical hypothyroidism and 19 healthy children were studied. Fasting plasma concentrations of tHCys and its putative determinants (plasma concentrations of free thyroxine [FT4], folate, vitamin B-12 and renal function) were measured. Results: tHCys concentrations showed no statistical difference between patients and controls (p >0.05). Moreover, the difference in tHCys and total cholesterol concentrations was not significant between patients with mild TSH elevations (less than or equal to10 mIU/l) and patients with prominent TSH elevations (>10 mIU/l). No correlation was found between tHCys concentrations and its putative determinants. Conclusions: We concluded that plasma tHCys concentrations were not increased in adolescent patients with subclinical hypothyroidism.en_US
dc.identifier.citationAtabek, M. E., Pirgon, Ö., Erkul, İ., (2003). Plasma Homocysteine Concentrations in Adolescents With Subclinical Hypothyroidism. Journal of Pediatric Endocrinology & Metabolism, 16(9), 1245-1248.
dc.identifier.endpage1248en_US
dc.identifier.issn0334-018Xen_US
dc.identifier.issue9en_US
dc.identifier.pmid1471-4746en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1245en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/18530
dc.identifier.volume16en_US
dc.identifier.wosWOS:000187795000006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAtabek, Mehmet Emre
dc.institutionauthorPirgon, Özgür
dc.institutionauthorErkul, İbrahim
dc.language.isoenen_US
dc.publisherFreund Publishing House Ltden_US
dc.relation.ispartofJournal of Pediatric Endocrinology & Metabolismen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectPlasma Total Homocysteineen_US
dc.subjectSubclinical Hypothyroidismen_US
dc.subjectAtherosclerosisen_US
dc.titlePlasma Homocysteine Concentrations in Adolescents With Subclinical Hypothyroidismen_US
dc.typeArticleen_US

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