Hippocampal cell loss after an anterior and posterior anastomotic vein occlusion model in rats

Basit Öğe Kaydı
dc.contributor.authorAydin, Keramettin
dc.contributor.authorCokluk, Cengiz
dc.contributor.authorAyas, Bulent
dc.contributor.authorOnger, Mehmet Emin
dc.contributor.authorKeskin, Ilknur
dc.contributor.authorOzyasar, Ali
dc.contributor.authorAslan, Huseyin
dc.date.accessioned2020-03-26T18:14:49Z
dc.date.available2020-03-26T18:14:49Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractEstimation of the cell number after cortical venous ischemia/infarction induced by anterior and posterior anastomotic veins occlusion in a rat model is very important. Twenty male Sprague-Dawley rats were used in this experiment. Small burr-holes were made over the anterior (the crossing point of the line drawn from the posterior border of the orbital rim and the line drawn along the para-midline to the superior sagittal suture) and posterior (just inferior point of the posterior ending of the zygomatic arch) anastomotic veins. Bipolar coagulation technique and micro-scissor were used to sacrifice the venous vessels after final inspection and description. Specimens were evaluated by histopathological and unbiased stereological methods for microscopic evaluation and volumetric analysis, respectively. Significant cell loss was seen in the pyramidal and granule cells of the cornu ammonis and dentate gyrus of the hippocampus after venous ischemia. Cell loss was also pronounced when seen in the histological examination. The present results suggest that the sacrifice of anterior and posterior anastomotic veins can be used as an experimental rat model in the evaluation of pyramidal and granule cell loss in the hippocampus that often assesses the neural damage inflicted by this intervention. (C) 2011 ISDN. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijdevneu.2011.05.013en_US
dc.identifier.endpage722en_US
dc.identifier.issn0736-5748en_US
dc.identifier.issue7en_US
dc.identifier.pmid21672620en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage717en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.ijdevneu.2011.05.013
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26532
dc.identifier.volume29en_US
dc.identifier.wosWOS:000296208400006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAnterior and posterior anastomotic venous occlusionen_US
dc.subjectHippocampal cell lossen_US
dc.subjectRat venous ischemia modelen_US
dc.subjectStereologyen_US
dc.titleHippocampal cell loss after an anterior and posterior anastomotic vein occlusion model in ratsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu