Alterations of Thyroid Hormone Levels in Cadmium Exposure

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dc.contributor.authorAkgöl, Evren
dc.contributor.authorTutkun, Engin
dc.contributor.authorYılmaz, Hinc
dc.contributor.authorYılmaz, Fatma Meriç
dc.contributor.authorGündüzöz, Meside
dc.contributor.authorBal, Ceylan Demir
dc.contributor.authorÜnlü, Ali
dc.date.accessioned2020-03-26T19:33:44Z
dc.date.available2020-03-26T19:33:44Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: Environmental chemicals and heavy metals may alter thyroid hormone levels via several mechanisms, including disruption of iodine (I) transport, thyroid peroxi-dase, thyroid hormone-binding proteins, hepatic catabolism, deiodinases, and receptor binding. Our aim was to investigate the change in thyroid hormone levels in cadmium exposure. Material and Method: Painters, welders, miners, and smelters with an occupational exposure of more than 10 years, aged between 18-70 years, were divided into six groups according to whole blood cadmium levels (Group 1: 0-0.5 mu g/L; Group 2: 0.5-1 mu g/L; Group 3: 1-1.5 mu g/L; Group 4: 1.5-2 mu g/L; Group 5: 2-2.5 mu g/L; Group 6: > 2.5 mu g/L). Results: There was a positive correlation between cadmium and serum free thyroxine and triiodothyronine levels. There was a negative correlation between cadmium and serum alanine aminotransferase and vitamin B12 levels. Discussion: Cadmium exposure was found to lead to an increase in thyroid hormone levels.en_US
dc.identifier.doi10.4328/JCAM.4802en_US
dc.identifier.endpage206en_US
dc.identifier.issn1309-0720en_US
dc.identifier.issn1309-2014en_US
dc.identifier.issue3en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage202en_US
dc.identifier.urihttps://dx.doi.org/10.4328/JCAM.4802
dc.identifier.urihttps://hdl.handle.net/20.500.12395/34775
dc.identifier.volume8en_US
dc.identifier.wosWOS:000402382500007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDERMAN MEDICAL PUBLen_US
dc.relation.ispartofJOURNAL OF CLINICAL AND ANALYTICAL MEDICINEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectCadmium Toxicityen_US
dc.subjectThyroid Functionsen_US
dc.subjectThyroxineen_US
dc.subjectWorkersen_US
dc.titleAlterations of Thyroid Hormone Levels in Cadmium Exposureen_US
dc.typeArticleen_US

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