Biological and chemical insights of Morina persica L.: A source of bioactive compounds with multifunctional properties

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dc.contributor.authorMocan, Andrei
dc.contributor.authorZengin, Gökhan
dc.contributor.authorUysal, Ahmet
dc.contributor.authorGüneş, Erdoğan
dc.contributor.authorMollica, Adriano
dc.contributor.authorDeğirmenci, Nurdan Sena
dc.contributor.authorAlpsoy, Lokman
dc.date.accessioned2020-03-26T19:23:12Z
dc.date.available2020-03-26T19:23:12Z
dc.date.issued2016
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractMorina persica L. has weak rosy smell flowers that together with aerial parts are infused or decocted and used as a functional tea. It is a representative of the Anatolian traditional medicine and is used for the treatment of cold. Biological and chemical fingerprints of different extracts (methanolic, acetone and water) of M. persica were investigated. Antioxidant, enzyme inhibitory, antimicrobial, cytotoxic and mutagenic/antimutagenic effects were evaluated for biological profiling. Rutin, chlorogenic and rosmarinic acids were detected as dominant compounds. Generally, the methanolic and acetone extracts had strong antioxidant, enzyme inhibitory, antimicrobial and antimutagenic effects. Additionally, all extracts showed remarkable inhibitory effects on HeLa cells at 100 mu g/mL. Furthermore, possible interactions between rutin, the dominant phenolic compound in M. persica and the tested enzymes were assessed by molecular docking. Results indicate that M. persica could be considered as a natural source of high-valued functional ingredients for further use in healthful formulations. (C) 2016 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.jff.2016.05.010en_US
dc.identifier.endpage109en_US
dc.identifier.issn1756-4646en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage94en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jff.2016.05.010
dc.identifier.urihttps://hdl.handle.net/20.500.12395/33310
dc.identifier.volume25en_US
dc.identifier.wosWOS:000381234200009en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofJOURNAL OF FUNCTIONAL FOODSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMorina persicaen_US
dc.subjectCytotoxicen_US
dc.subjectNatural agentsen_US
dc.subjectRutinen_US
dc.subjectFunctional ingredientsen_US
dc.titleBiological and chemical insights of Morina persica L.: A source of bioactive compounds with multifunctional propertiesen_US
dc.typeArticleen_US

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