Vernal keratoconjunctivitis-A rare but serious comorbidity of allergic rhinitis and eustachian tube dysfunction

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dc.contributor.authorBozkurt, M. K.
dc.contributor.authorBozkurt, B.
dc.contributor.authorArtac, H.
dc.contributor.authorArslan, N.
dc.contributor.authorReisli, I.
dc.date.accessioned2020-03-26T18:05:33Z
dc.date.available2020-03-26T18:05:33Z
dc.date.issued2010
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: To determine the prevalence of symptoms and signs of allergic rhinitis (AR) in children with vernal keratoconjunctivitis (VKC) and evaluate eustachian tube (ET) function using tympanometry. Methods: The patients underwent an otolaryngological examination and symptoms of rhinorrhoea, nasal obstruction, nasal itching and sneezing were evaluated for the diagnosis of AR. Tympanometry was performed by a middle ear analyzer (Impedance audiometer AZ 26, Interacoustics A/S, Assens, Denmark). Blood samples were collected for determination of peripheral blood eosinophil count (PBEC) and serum total immunoglobulin E (IgE). Allergen sensitivity was also determined by skin prick test. Results: The study included 26 males (96.3%) and 1 female (3.7%) with a mean age of 12.1 +/- 4.4 years. Eight out of 27 subjects (29.6%) had blood eosinophilia and 11 out of 27 subjects had elevated serum IgE (40.7%). A positive skin prick test was identified for at least one allergen in 40% of patients (10/25 subjects). Symptoms and signs of AR were found in 10 subjects (37%). Median serum IgE level in subjects with AR (262.5 kU/L)was higher than without AR(40.2 kU/L)(p = 0.08),whereas there were no differences in PBEC or eosinophilia percentage (p > 0.05). Mean middle ear pressures in the right and left ears were -66.4 daPa (range between -268 and 4 daPa) and -57.3 daPa (range between -308 and 0 daPa), respectively. The tympanometry results were abnormal in 5 subjects (18.5%) (3 type C and 2 type B tympanogram). Three out of 10 VKC patients with AR (30%) and 2 out of 17 VKC patients without AR (11.8%) had abnormal tympanograms (p = 0.33). Conclusion: AR is commonly associated with VKC and subjects with AR are almost three times more likely to have ET dysfunction than those without. Therefore, opthalmologists should refer VKC patients to otolaryngologists to delineate associated AR and ET dysfunction. Conversely, patients with OME and/or AR who have persistent allergic eye symptoms may well benefit from opthalmologic evaluation for seasonal allergic conjunctivitis and VKC. (C) 2009 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijporl.2009.10.011en_US
dc.identifier.endpage63en_US
dc.identifier.issn0165-5876en_US
dc.identifier.issn1872-8464en_US
dc.identifier.issue1en_US
dc.identifier.pmid19900723en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.ijporl.2009.10.011
dc.identifier.urihttps://hdl.handle.net/20.500.12395/25462
dc.identifier.volume74en_US
dc.identifier.wosWOS:000273901800012en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER IRELAND LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectVernal keratoconjunctivitisen_US
dc.subjectAllergic rhinitisen_US
dc.subjectTympanogramen_US
dc.subjectImmunoglobulin Een_US
dc.subjectEustachian tube dysfunctionen_US
dc.titleVernal keratoconjunctivitis-A rare but serious comorbidity of allergic rhinitis and eustachian tube dysfunctionen_US
dc.typeArticleen_US

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