Investigation of serum nitric oxide, oxidized low density lipoprotein and total antioxidant activity in obese subjects and healthy controls

Basit Öğe Kaydı
dc.contributor.authorYerlikaya, Huemeyra F.
dc.contributor.authorMehmetoglu, Idris
dc.contributor.authorKurban, Sevil
dc.contributor.authorYilmaz, Guelsuem
dc.date.accessioned2020-03-26T17:27:06Z
dc.date.available2020-03-26T17:27:06Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: Obesity which is defined as a disease characterized by increased lipid tissue and excessive lipid storage in the body, is not only a basic esthetic problem but also a chronic disease which has bad effects on physiological and physiciatric health. The etiopathogenesis of obesity is not exactly known. In this study, we aimed to investigate serum nitric oxide (NO), oxidized low density lipoprotein (Ox-LDL) and total antioxidant activity (TAA) of obese sucjects to determine the role of these parameteres on the etiopathogenesis of the disease. Material and Methods: This study was performed on 33 obese subjects (8 M, 25 F; aged 29-69 years) and 30 healty control (16 M, 14 F; aged 28-69 years). Those with body mass index (BMI) more than 35 kg/m(2) was considered as obese. Serum NO, Ox-LDL and TAA levels of both groups were measured. Results: Serum NO and Ox-LDL levels of the obese subjects were higher than those of the controls whereas serum TAA levels of obese subjects was lower than that of the controls. But the differences between the parameters were not statistically significant. Also, there was no significant correlation between BMI and NO, Ox-LDL and TAA levels in both groups. Conclusion: We found no significant differences between serum NO, Ox-LDL and TAA levels of obese subjects and healty controls and no significant correlation between BMI and above parameters of the subjects. This shows that oxidative stress was not changed in obese people compared to healthy controls which needs to be more investigated.en_US
dc.identifier.endpage127en_US
dc.identifier.issn1300-0292en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage123en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22474
dc.identifier.volume28en_US
dc.identifier.wosWOS:000256246600002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherORTADOGU AD PRES & PUBL COen_US
dc.relation.ispartofTURKIYE KLINIKLERI TIP BILIMLERI DERGISIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectobesityen_US
dc.subjectnitric oxideen_US
dc.subjectoxidized low density lipoproteinen_US
dc.subjectoxidative stressen_US
dc.titleInvestigation of serum nitric oxide, oxidized low density lipoprotein and total antioxidant activity in obese subjects and healthy controlsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu