Comparison of two different radiotherapy techniques in stomach cancer paiients who underwent concomitant chemoradiotherapy

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dc.contributor.authorYavaş, Güler
dc.contributor.authorYavaş, Çağdaş
dc.contributor.authorÇobanoğlu, Gökçen
dc.contributor.authorGül, Osman Vefa
dc.contributor.authorAcar, Hilal
dc.contributor.authorAta, Özlem
dc.date.accessioned2020-03-26T18:58:49Z
dc.date.available2020-03-26T18:58:49Z
dc.date.issued2014
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: We aimed to compare four field radiotherapy techniques with three field radiotherapy technique with enhanced dynamic wedges (EDW) in patients with stomach cancer who underwent postoperative chemo-radiotherapy. Material and Methods: Ten consecutive stomach cancer patients who underwent total/subtotal gastrectomy and lymph node dissection were included to the study. For each patient, two different treatment plans were created for the tumor bed and regional lymph nodes. Three field and four field plans were compared for the doses in the planning target volume (PTV), the organ at risk (OAR) volumes (including kidneys, liver, spleen and spinal cord), the dose homogeneity index (DHI), and the monitor unit counts (MU) required for the treatment. Student-t test was used for statistical analysis. Results: There was no difference between two techniques in terms of DHI (p:0.576). The mean dose received by the liver was significantly reduced with three field technique (p<0.001); whereas the mean doses of the kidneys, spleen and spinal cord were decreased with four field technique (p values were 0.007, 0.021 and <0.001 respectively). The dose to %10, %30, %40 and %50 of the total liver volume were significantly reduced with three field technique (p values were 0.026, 0.009, 0.001 and <0.001 respectively). The MU counts required for the treatment was significantly lower with four filed technique (p<0.001). Conclusion: There weren't any difference in terms of dose homogeneity in the PTV and DHI between four field technique and three field techniques with EDW in patients with stomach cancer who underwent radiotherapy to the tumor bed and regional lymph nodes. It was expected to need more MU in the three field technique with EDW. The liver dose was significantly reduced with three field technique. Therefore it is more convenient to choose three field techniques with EDW in patients with known liver disease.en_US
dc.identifier.doi10.5350/BTDMJB201410103en_US
dc.identifier.endpage17en_US
dc.identifier.issn1305-9327en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage11en_US
dc.identifier.urihttps://dx.doi.org/10.5350/BTDMJB201410103
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31302
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherGalenos Publishing Houseen_US
dc.relation.ispartofMedical Journal of Bakirkoyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectDose volume histogramsen_US
dc.subjectRadiotherapyen_US
dc.subjectStomach canceren_US
dc.titleComparison of two different radiotherapy techniques in stomach cancer paiients who underwent concomitant chemoradiotherapyen_US
dc.title.alternativeMide kanseri nedeni ile eş zamanlı kemoradyoterapi uygulanan hastalarda iki farklı radyoterapi tekniğinin karşılaştırılması
dc.typeArticleen_US

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