Oxidative stress and antioxidant status in bronchoalveolar lavage fluid, plasma and erythrocyte of critically mixed ill with respiratory failure

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dc.contributor.authorBüyükbaş S.
dc.contributor.authorUzun K.
dc.contributor.authorDemirkapi E.
dc.contributor.authorBaşarali K.
dc.date.accessioned2020-03-26T17:29:02Z
dc.date.available2020-03-26T17:29:02Z
dc.date.issued2008
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractAim: Increased oxidative stress is a significant part of pathogenesis of various lung diseases. In this trial, it is aimed to determine the role of oxidative stress in patients receiving mechanical ventilation for respiratory failure (RF). Methods: The oxidative stress was evaluated by determining plasma, bronchial fluid and erythrocyte levels of malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), ascorbic acid, alpha-tocopherol, uric acid (UA) and nitric oxide (NO) in 25 critically ill patients with RF. Twenty five patients without RF was evaluated as control group. Results: Oxidative stress (MDA, NO) levels of plasma, erythrocyte and BAL fluid in mixed critically ill with respiratory failure were higher than control group. Antioxidant levels of plasma, erythrocyte and BAL fluid in mixed critically ill with respiratory failure were lower than control group. In all parameters, there was no statistically difference as exitus and survivors in critically mixed patients. Conclusion: Oxidative stress was higher in respiratory failure than control group.en_US
dc.identifier.endpage146en_US
dc.identifier.issn1304-3889en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage140en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12395/22897
dc.identifier.volume5en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofEuropean Journal of General Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAntioxidant statusen_US
dc.subjectOxidative stressen_US
dc.subjectRespiratory failureen_US
dc.titleOxidative stress and antioxidant status in bronchoalveolar lavage fluid, plasma and erythrocyte of critically mixed ill with respiratory failureen_US
dc.typeArticleen_US

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