Evaluation of pathological changes in broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposure

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dc.contributor.authorOrtatatli, M
dc.contributor.authorOguz, H
dc.contributor.authorHatipoglu, F
dc.contributor.authorKaraman, M
dc.date.accessioned2020-03-26T16:57:11Z
dc.date.available2020-03-26T16:57:11Z
dc.date.issued2005
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThis study was conducted to evaluate the pathological changes in broilers fed a diet containing low-levels of aflatoxin (AF) and clinoptilolite (CLI) until 42 days of age. A total of 576 one-day-old Ross-308 type broiler chicks were treated with varying levels of AF and CLI (15 g kg(-1)). The gross and histopathological changes in the liver, kidneys, spleen, thymus and bursa of Fabricius were investigated and relative organ weights were calculated. Compared to controls, significant changes (P < 0.05), such as slight to moderate hydropic degeneration and/or fatty change (8 cases of 10), bile-duct hyperplasia (7 of 10) and periportal fibrosis (5 of 10), were found in chicks fed 100 ppb AF-containing diet. No gross-pathological changes were observed in any treatments. The addition of CLI to the 100 ppb AF-containing diet significantly decreased the number of affected broilers and/or the severity of lesions (hydropic degeneration and bile-duct hyperplasia) in the livers (P < 0.05). The addition of CLI to the AF-free diet did not produce any significant lesions compared with the controls. (C) 2004 Published by Elsevier Ltd.en_US
dc.identifier.doi10.1016/j.rvsc.2004.06.006en_US
dc.identifier.endpage68en_US
dc.identifier.issn0034-5288en_US
dc.identifier.issn1532-2661en_US
dc.identifier.issue1en_US
dc.identifier.pmid15500841en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage61en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.rvsc.2004.06.006
dc.identifier.urihttps://hdl.handle.net/20.500.12395/19734
dc.identifier.volume78en_US
dc.identifier.wosWOS:000226425400010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherELSEVIER SCI LTDen_US
dc.relation.ispartofRESEARCH IN VETERINARY SCIENCEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.titleEvaluation of pathological changes in broilers during chronic aflatoxin (50 and 100 ppb) and clinoptilolite exposureen_US
dc.typeArticleen_US

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