Effects of Zinc and Melatonin Deficiency on Testicular Tissue of Rats

Yükleniyor...
Küçük Resim

Tarih

2003

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Humana Press Inc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

The present study was designed to investigate the effects of zinc and/or melatonin deficiency on rat testes. A total of 24 adult male Sprague-Dawley rats were used in this study The rats were divided into four groups of six rats each, as follows: (I) controls, (II) zinc deficient, (III) pinealectomized, zinc normal, and (IV) pinealectomized, zinc deficient. The plasma zinc levels in the control group were higher than in all the other groups (p < 0.01), and those of the zinc-deficient groups II and IV were significantly lower than for group III (p < 0.01). The melatonin levels in the controls were also significantly higher than for all other groups (p < 0.01) There was no significant difference in sperm production between the controls and the group of animals that had no epiphysis. A significant suppression was observed in the spermatogenetic activity of the zinc-deficient groups (p < 0.01). The suppression was higher in group II than in group IV. These results indicate that testicular damage caused by zinc deficiency may be reduced by melatonin deficiency.

Açıklama

Anahtar Kelimeler

Melatonin, Pinealectomy, Rats, Testes, Zinc Deficiency

Kaynak

Biological Trace Element Research

WoS Q Değeri

Q4

Scopus Q Değeri

Q1

Cilt

96

Sayı

Künye

Öztürk, A., Baltacı, A. K., Bediz, C. Ş., Moğulkoç, R., Güngör, S., (2003). Effects of Zinc and Melatonin Deficiency on Testicular Tissue of Rats. Biological Trace Element Research, (96), 255-262. Doi: 10.1385/BTER:96:1-3:255