Investigation of the Relationship between Serum Levels of Cotinine and the Renal Function in Active and Passive Smokers

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dc.contributor.authorDulger, Haluk
dc.contributor.authorDonder, Ahmet
dc.contributor.authorSekeroglu, Mehmet Ramazan
dc.contributor.authorErkoc, Reha
dc.contributor.authorOzbay, Bulent
dc.date.accessioned2020-03-26T18:15:01Z
dc.date.available2020-03-26T18:15:01Z
dc.date.issued2011
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractObjective: We have investigated the effects of active and passive smoking on renal functions in terms of glomerular filtration rate, microalbuminuria, and beta-2 microglobulin excretion. Design and method: The volunteers included in this study were classified into three groups as active smokers (n = 24), passive smokers (n = 20), and controls (n = 20). Blood and urine samples were collected from all groups. Serum glucose, urea, creatinine, and cotinine levels in the collected blood samples were measured. Also, microalbumin, beta-2 microglobulin, and creatinine levels were measured in the collected urine samples. Results: Serum cotinine levels were found to be higher in both passive and active smokers when compared with controls (p < 0.01), whereas urinary microalbumin and creatinine levels were significantly higher in active smokers (p < 0.01). The urinary microalbumin/creatinine ratio was significantly increased in both active and passive smokers compared with controls. Conclusion: The kidney and the glomerular functions may be affected even by passive smoking. In addition, increased microalbumin/creatinine ratio may be a sign of increased atherosclerosis risk in these persons.en_US
dc.identifier.doi10.3109/0886022X.2011.577922en_US
dc.identifier.endpage479en_US
dc.identifier.issn0886-022Xen_US
dc.identifier.issue5en_US
dc.identifier.pmid21574894en_US
dc.identifier.startpage475en_US
dc.identifier.urihttps://dx.doi.org/10.3109/0886022X.2011.577922
dc.identifier.urihttps://hdl.handle.net/20.500.12395/26586
dc.identifier.volume33en_US
dc.identifier.wosWOS:000290670300002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherINFORMA HEALTHCAREen_US
dc.relation.ispartofRENAL FAILUREen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectActive smokersen_US
dc.subjectpassive smokersen_US
dc.subjectmicroalbuminuriaen_US
dc.subjectbeta-2 microglobulinen_US
dc.subjectcotinineen_US
dc.titleInvestigation of the Relationship between Serum Levels of Cotinine and the Renal Function in Active and Passive Smokersen_US
dc.typeArticleen_US

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