Pharmacological Activities, Chemical Profile, and Physicochemical Properties of Raw and Commercial Honey

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dc.authorid0000-0002-8901-6484
dc.contributor.authorAumeeruddy, M. Z.
dc.contributor.authorElalfi, Zaahira Aumeeruddy
dc.contributor.authorNeetoo, H.
dc.contributor.authorZengin, Gökhan
dc.contributor.authorvan Staden, Analike Blom
dc.contributor.authorFibrich, Bianca
dc.contributor.authorLambrechts, Isa A.
dc.contributor.authorRademan, Sunelle
dc.contributor.authorSzuman, Karina M.
dc.contributor.authorLall, Namrita
dc.contributor.authorMahomoodally, Mohamad Fawzi
dc.date.accessioned2020-03-26T20:19:07Z
dc.date.available2020-03-26T20:19:07Z
dc.date.issued2019
dc.departmentSelçuk Üniversitesi, Fen Fakültesi, Biyoloji Bölümüen_US
dc.description.abstractThis study was designed to evaluate and correlate the pharmacological, phytochemical, and physicochemical properties of raw unifloral Mauritian eucalyptus honey (EH) and a commercially available honey (CH). The pharmacological activity was evaluated in terms of antibacterial, antioxidant (nitric oxide scavenging), antielastase, antityrosinase, antimelanogenic, and anticancer activity (MCF-7 and HeLa cell toxicity). The presence of phytochemicals including alkaloids, flavonoids, saponins, phenols, anthraquinones, and steroids were determined along with the total phenolic (TPC), total flavonoid (TFC), and tannin content (TC). Physicochemical properties including the pH, colour, total soluble solids, and density were also investigated. The results showed that EH displayed greater antibacterial, antioxidant, and anticancer activity against the MCF-7 cell line compared to CH, which also showed higher extracellular antimelanogenic activity. MH (IC50 = 532.75 mu g/ml) displayed significantly greater scavenging activity than CH (IC50 = 647.6 mu g/ml). To conclude, honey may be potentially exploited as complementary and alternative therapies for the management of infectious and chronic diseases.en_US
dc.identifier.citationAumeeruddy, M. Z., Aumeeruddy-Elalfi, Z., Neetoo, H., Zengin, G., van Staden, A. B., Fibrich, B., Lambrechts, I. A., Rademan, S., Szuman, K. M., Lall, N., Mahomoodally, F. (2019). Pharmacological Activities, Chemical Profile, and Physicochemical Properties of Raw and Commercial Honey. Biocatalysis and Agricultural Biotechnology, 18, 101005. doi: https://dx.doi.org/10.1016/j.bcab.2019.01.043
dc.identifier.doi10.1016/j.bcab.2019.01.043en_US
dc.identifier.issn1878-8181en_US
dc.identifier.pmid#YOKen_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.bcab.2019.01.043
dc.identifier.urihttps://hdl.handle.net/20.500.12395/38089
dc.identifier.volume18en_US
dc.identifier.wosWOS:000469474200011en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorZengin, Gökhan
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofBiocatalysis and Agricultural Biotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectMauritiusen_US
dc.subjectAnticanceren_US
dc.subjectAntimelanogenicen_US
dc.subjectAntibacterialen_US
dc.subjectAntioxidanten_US
dc.subjectAntielastaseen_US
dc.subjectAntikanser
dc.subjectAntimelanojenik
dc.subjectAntibakteriyel
dc.subjectAntioksidan
dc.subjectAntielastaz
dc.titlePharmacological Activities, Chemical Profile, and Physicochemical Properties of Raw and Commercial Honeyen_US
dc.typeArticleen_US

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