Biocompatible multi-walled carbon nanotube-CdTe quantum dot-polymer hybrids for medical applications

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dc.contributor.authorBaşlak, Canan
dc.contributor.authorKars, Meltem Demirel
dc.contributor.authorKaraman, Mustafa
dc.contributor.authorKuş, Mahmut
dc.contributor.authorÇengeloğlu, Yunus
dc.contributor.authorErsöz, Mustafa
dc.date.accessioned2020-03-26T19:01:06Z
dc.date.available2020-03-26T19:01:06Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractHerein we report the synthesis of polymer coated quantum dots (QDs)-carbon nanotube composite material with high biocompatibility and low cellular toxicity. The synthesized multi-walled carbon nanotube (MWCNT)-QD-(-poly(glycidyl methacrylate)) (pGMA) hybrids were characterized using X-ray photoelectron spectroscopy, laser scanning confocal microscopy, transmission electron microscopy and scanning electron microscopy. The results showed that quantum dots were well-distributed on nanotube surfaces in high density. The toxicological assessments of QDs and MWCNT-QD-polymer hybrids in human mammary carcinoma cells and their fluorescence imaging in living cell system were carried out. MWCNT-QD-polymer hybrids possess intense red fluorescence signal under confocal microscopy and good fluorescence stability over 6-h exposure in living cell system. The toxicity comparison of QDs and MWCNT-QD-polymer hybrids has shown that the existence of PGMA thin coating on MWCNT-QD hybrid surface decreased the cellular toxicity and increased biocompatibility. (C) 2014 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipSelcuk University CorporationSelcuk University [11101015]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113Z254]en_US
dc.description.sponsorshipThe authors would like to thank Selcuk University Corporation (Grant no.11101015) and TUBITAK (Project no. 113Z254) for financially supporting this work.en_US
dc.identifier.doi10.1016/j.jlumin.2014.11.030en_US
dc.identifier.endpage15en_US
dc.identifier.issn0022-2313en_US
dc.identifier.issn1872-7883en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage9en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.jlumin.2014.11.030
dc.identifier.urihttps://hdl.handle.net/20.500.12395/31890
dc.identifier.volume160en_US
dc.identifier.wosWOS:000350087100002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofJOURNAL OF LUMINESCENCEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectQuantum dotsen_US
dc.subjectCarbon nanotubesen_US
dc.subjectCNT-QD hybridsen_US
dc.subjectBiocompatibilityen_US
dc.subjectLive cell imagingen_US
dc.titleBiocompatible multi-walled carbon nanotube-CdTe quantum dot-polymer hybrids for medical applicationsen_US
dc.typeArticleen_US

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