Comparison of instilled lidocaine and procaine effects on pain relief in dogs undergoing elective ovariohysterectomy

The aim of the present study was to compare the analgesic efficacy of instilled intra-peritoneal lidocaine and procaine during the perioperative and the postoperative periods in dogs undergoing elective ovariohysterectomy (OVH). Twenty-four sexually intact female dogs were referred for OVH. Following the laparotomv procedure the L group received intraperironeal instillation of 3.5 mg/kg of 0.2% lidocaine. The therapeutic agent was administreted over the area of ovaries, broad ligament, and uterine stump. It was injected using a syringe and needle (23 G). The P group administered intraperitoneal instillation of 3.5 mg/kg of 0.2% procaine and the control group received 1.75 ml/kg of intraperitoneal saline in a similar fashion. Groups L and P had significantly lower Glascow Composite Measure Pain Scale scores (CMPS-SF) than the control group at the 0.5, 1,2, 3, 8, and 24 hour postoperative periods. In conclusion, administerstration of intraperitoneal installation of lidocaine and procaine were shown to provide a milady significant effect in reducing intraoperative and postoperative pain and biochemical stress responses within 3 hours of surgery.