In Vitro Activity of Toxin Binders on Aflatoxin B1 in Poultry Gastrointestinal Medium

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dc.contributor.authorYalcin, Nihayet Fadime
dc.contributor.authorAvci, Tulay
dc.contributor.authorIsik, Mehmet Kursat
dc.contributor.authorOguz, Halis
dc.date.accessioned2020-03-26T19:54:18Z
dc.date.available2020-03-26T19:54:18Z
dc.date.issued2018
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe purpose of this study was to determine the effectiveness of organic, inorganic and mixed toxin binders (TB) commonly used in poultry feeds to bind aflatoxin B1 (AFB1) in in vitro conditions. A total of 20 TBs, which were commonly used in the poultry industry, were divided into three groups as organic, inorganic and mix according to their contents. For each TB was used in in vitro poultry mediums both at pH 3 and 6.8 to represent proventriculus and intestine of poultry, respectively. Control groups were prepared from standard AFB1 and its dilutions; and the treatment groups were prepared from TBs (10mg) and standard AFB1 and its dilutions. After mixing and incubation periods, the samples (8 control, 6 organic, 6 inorganic and 8 mix) were analyzed in 4 replicates (2 for pH 3 and 2 for 6.8) by the method of Vicam aflatest method in HPLC-FLD after extraction and filtration processes. The binding capacity of inorganic TBs was found to be the highest, 98 and 93% at pH 3.0 and 6.8 while the organic TBs were the lowest, 40 and 45% at pH 3.0 and 6.8 respectively. Likewise, the binding capacity of mix TBs to AFB1 was found 96 and 88% at pH 3.0 and 6.8 in in vitro conditions. It was concluded that the inorganic and mix TBs were found to be effective to bind AFB1 among the TBs and could be applied to reduce the negative effects of AFB1 in poultry feeds. The organic TBs were found to be not sufficient to bind AFB1. (C) 2017 PVJ. All rights reserveden_US
dc.description.sponsorshipMinistry of Food, Agriculture and LivestockGida Tarim Ve Hayvancilik Bakanligi [TAGEM-HSGYAD 14/AO5/PO4/69]en_US
dc.description.sponsorshipThis study was funded by Ministry of Food, Agriculture and Livestock; Project no: TAGEM-HSGYAD 14/AO5/PO4/69. This paper was presented as a poster in 32nd World Veterinary Congress, 13-17 September 2015, Istanbul, Turkey.en_US
dc.identifier.doi10.29261/pakvetj/2018.012en_US
dc.identifier.endpage65en_US
dc.identifier.issn0253-8318en_US
dc.identifier.issn2074-7764en_US
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage61en_US
dc.identifier.urihttps://dx.doi.org/10.29261/pakvetj/2018.012
dc.identifier.urihttps://hdl.handle.net/20.500.12395/36702
dc.identifier.volume38en_US
dc.identifier.wosWOS:000427222100012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherUNIV AGRICULTURE, FAC VETERINARY SCIENCEen_US
dc.relation.ispartofPAKISTAN VETERINARY JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectAflatoxinen_US
dc.subjectBinding activityen_US
dc.subjectIn vitroen_US
dc.subjectPoultry mediumen_US
dc.titleIn Vitro Activity of Toxin Binders on Aflatoxin B1 in Poultry Gastrointestinal Mediumen_US
dc.typeArticleen_US

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