Salvia nemorosa L.: A novel source of bioactive agents with functional connections

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dc.contributor.authorBahadori, Mir Babak
dc.contributor.authorAsghari, Behvar
dc.contributor.authorDinparast, Leila
dc.contributor.authorZengin, Gökhan
dc.contributor.authorSarıkürkcü, Cengiz
dc.contributor.authorAbbas-Mohammadi, Mahdi
dc.contributor.authorBahadori, Shahram
dc.date.accessioned2020-03-26T19:42:33Z
dc.date.available2020-03-26T19:42:33Z
dc.date.issued2017
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractSalvia species are used as food and medicinal plants all around the world. In this study, chemical composition and antimicrobial, toxicity, antioxidant, and enzyme inhibitory activity of Salvia nemorosa were evaluated. Phenolic components were characterized by the HPLC-DAD and 11 components were identified, in which rosmarinic acid was detected as the major compound (7584 mu g/g extract). Sixteen volatile components were determined in both leaves and flowers essential oils. Oxygenated sesquiterpenes were the major components. Methanolic extract showed the highest total phenolic and flavonoid contents (294 mg GAE/g and 117 mg QE/g extract, respectively) and the strongest DPPH radical scavenging activity (IC50: 82 mu g/mL). Plant samples showed moderate to high aldehyde oxidase, xanthine oxidase, acetylcholinesterase, and alpha-glucosidase inhibitory activity and moderate cytotoxicity. Also, EOs exhibited great antimicrobial potential (IZ: 8.8-33.7 mm). Our findings indicated that S. nemorosa may be useful for novel applications in functional food and pharmaceutical industries. (C) 2016 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.lwt.2016.08.048en_US
dc.identifier.endpage50en_US
dc.identifier.issn0023-6438en_US
dc.identifier.issn1096-1127en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage42en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.lwt.2016.08.048
dc.identifier.urihttps://hdl.handle.net/20.500.12395/35454
dc.identifier.volume75en_US
dc.identifier.wosWOS:000387518800006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherELSEVIER SCIENCE BVen_US
dc.relation.ispartofLWT-FOOD SCIENCE AND TECHNOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectSalviaen_US
dc.subjectAcetylcholinesteraseen_US
dc.subjectDiabetes mellitusen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectPhenolicsen_US
dc.titleSalvia nemorosa L.: A novel source of bioactive agents with functional connectionsen_US
dc.typeArticleen_US

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