EVALUATION OF THE CHITOSAN-COATING EFFECTIVENESS ON A DENTAL TITANIUM ALLOY IN TERMS OF MICROBIAL AND FIBROBLASTIC ATTACHMENT AND THE EFFECT OF AGING

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dc.contributor.authorKalyoncuoğlu, Ülkü Tuğba
dc.contributor.authorYılmaz, Bengi
dc.contributor.authorGüngör, Serap
dc.contributor.authorEvis, Zafer
dc.contributor.authorUyar, Pembegül
dc.contributor.authorAkça, Gülçin
dc.contributor.authorKansu, Gülay
dc.date.accessioned2020-03-26T19:05:57Z
dc.date.available2020-03-26T19:05:57Z
dc.date.issued2015
dc.departmentSelçuk Üniversitesien_US
dc.description.abstractThe aim of this study was to obtain a biocompatible and antimicrobial implant surface by coating Ti6Al4V with chitosan which can be used to create a smooth transmucosal region for a faster and better wound healing and an increased bioactivity. Ti6Al4V plates were first abraded and ultrasonically cleaned and then coated with chitosan. In order to simulate the conditions of an oral environment, a group of coated plates were treated in a thermocycle apparatus. The coatings were evaluated with SEM, EDS, XRD and FTIR spectroscopy. The fibroblastic cell behavior was determined using HGF-1 cells. P. gingivalis was used to assess the effectiveness of chitosan as an antimicrobial coating. It can be said that the Ti6Al4V plates were successfully coated with chitosan, indicated by the presence of the C, H and O elements in the EDS results. There were no significant differences between the XRD patterns of the coated and uncoated plates; however, the characteristic bands of chitosan were observed in the FTIR patterns of both the coated and aged samples. The fibroblast-cell attachment and proliferation were enhanced while the bacterial proliferation was inhibited by the chitosan coating. Chitosan was shown to be a biologically useful material that can be used as the coating material for transmucosal regions of dental implants.en_US
dc.description.sponsorshipTUBITAK (the Scientific and Technological Research Council of Turkey)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [111S515]en_US
dc.description.sponsorshipThis research was supported by TUBITAK (the Scientific and Technological Research Council of Turkey) through project 111S515. The authors would also like to thank the Advanced Technology Research and Application Center at the Selcuk University for providing the resources (the cell culture and SEM facilities) necessary for the completion of this work.en_US
dc.identifier.doi10.17222/mit.2014.239en_US
dc.identifier.endpage931en_US
dc.identifier.issn1580-2949en_US
dc.identifier.issn1580-3414en_US
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage925en_US
dc.identifier.urihttps://dx.doi.org/10.17222/mit.2014.239
dc.identifier.urihttps://hdl.handle.net/20.500.12395/32135
dc.identifier.volume49en_US
dc.identifier.wosWOS:000366552500012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherINST ZA KOVINSKE MATERIALE I IN TEHNOLOGIEen_US
dc.relation.ispartofMATERIALI IN TEHNOLOGIJEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.selcuk20240510_oaigen_US
dc.subjectchitosan coatingen_US
dc.subjectdental implantsen_US
dc.subjectTi6Al4Ven_US
dc.subjectHGF-1en_US
dc.subjectP. gingivalisen_US
dc.titleEVALUATION OF THE CHITOSAN-COATING EFFECTIVENESS ON A DENTAL TITANIUM ALLOY IN TERMS OF MICROBIAL AND FIBROBLASTIC ATTACHMENT AND THE EFFECT OF AGINGen_US
dc.typeArticleen_US

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