Antimycotic activity of methanol extracts of sage (Salvia officinalis L.), Laurel (Laurus Nobilis L.) and Thyme (Thymbra spicata L.)

Inhibitory effects of methanol-water (90: 10; v/v) extract from sage (Salvia officinalis L.), laurel (Laurus nobilis L.) and thyme (Thymbra spicata L.) were tested in vitro on clinical isolates of eleven species of yeasts (C. krusei, C. clus, Rhodotorula rubra, C. albicans 10039, C. tropicalis, C. glabrata 70164, C. parasilosis, C. insane, C. rhodotonla, C. holmii and C. glabrata 13b). Preliminary experiment was carried out in vitro using the disc diffusion method to investigate antimycotic activity of the sage, laurel and thyme extracts. Thyme methanol extract showed very high antimycotic activity against all tested yeasts. Effect of laurel extract was as good as thyme extract for C. tropicalis at 40 ppm level. Generally, sage had no effect on the tested yeasts. Methanol extracts of thyme and laurel may be useful tools to control the yeasts growth.