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Öğe The effects of risk factors on EEG and seizure in children with ADHD(SPRINGER HEIDELBERG, 2017) Kartal, Ayse; Aksoy, Erhan; Deda, GuelhisAttention-deficit hyperactivity disorder (ADHD) is one of the most commonly seen developmental disorders in childhood. Its etiology, however, is not well known even though bio-psycho-social reasons have been thought to play a big role. The aims of this retrospective study are to identify the risk factors of ADHD in patients diagnosed with ADHD in childhood, analyze the relationship between clinical symptoms and risk factors to which they were exposed and determine their effects on prospective electrophysiological findings. Longitudinal cohort study of all children with ADHD treated at Ankara University Medical University during 2007-2012, with follow-up to ascertain risk factors and seizure and EEG abnormalities outcome. Multinominal univariate logistic regression analysis was used to calculate adjusted risk ratios (RRs) and 95% confidence intervals (CIs) for associations. Epileptiform discharges were found in 32 (22.9%) of the 140 ADHD patients. Of these, 71.9% had focal epileptiform discharges and 28.1% had generalized epileptiform discharges. The focal epileptiform discharges were most prevalent from the rolandic area. Among the 140 patients, 20 (14.3%) had a previous history of seizure, and all twenty had epileptiform discharges on EEG whereas none of the patients who had normal EEG had a seizure history. The rates of epileptiform discharges were significantly related to gestational age and asphyxia (RR: 1.8, 95% CI 0.3, 9.3; RR: 9.6, 95% CI 2.3, 40, respectively), whereas the rates of epilepsy were related to asphyxia but not gestational age. History of asphyxia and prematurity do seem to increase the risk of EEG abnormality in patients with ADHD. Modification of these environmental risk factors by evidence-based prevention programs may help to decrease the burden of ADHD.Öğe Evaluation of Visual Evoked Potentials in Children with Neurofibromatosis Type 1 and Comparison With Radiological Findings(Selçuk Üniversitesi, 2023 Şubat) Öztoprak, Ülkühan; Aksoy, Erhan; Ceylan, Nesrin; Ekşioğlu, Ayşe Seçil; Yüksel, DenizDergimizin 2022 yılı 32. Cilt 2. Sayısında 144-149 sayfa aralığında yayımlanan "Nörofibromatozis Tip 1 Tanılı Çocuklarda Desen Görsel Uyarılmış Potansiyellerin Değerlendirilmesi ve Radyolojik Bulgularla Karşılaştırılması" başlıklı makalenin erken görünüm aşamasında Gereç ve Yöntem kısmında çalışmanın yapıldığı merkez adı xxxxxxxxxxxxx şeklinde boş bırakılmış, tablo ve figür başlıkları da Türkçe olacak şekilde sehven hatalı olarak yayına alınmıştır. Makalede yer alan hataların giderilmesi için makale tekrardan sunulmuştur.Öğe Evaluation of Visual Evoked Potentials in Children with Neurofibromatosis Type 1 and Comparison With Radiological Findings(Selçuk Üniversitesi, 2022) Öztoprak, Ülkühan; Aksoy, Erhan; Ceylan, Nesrin; Ekşioğlu, Ayşe Seçil; Yüksel, DenizPurpose: It was aimed to examine the pattern visual evoked potentials (P-VEP) of children with neurofibromatosis type 1 (NF type 1) and to evaluate the correlation of P-VEP results with optical gliomas and unidentified bright objects (UBO) associated with NF Type 1. Materials and Methods: P-VEP and P100 latencies of 28 children including 16 (%57) boys, who were followed up with the diagnosis of NF Type 1 in the Pediatric Neurology Outpatient Clinic of xxxxxxxxxxxxx between 2017 and 2020, with a mean age of 9.61 ± 3.7 years of age were compared with the P100 latencies of a control group consisting of 28 healthy children of similar age and gender. Results: Unidentified bright objects were found in the brain of 82% of the patients by using magnetic resonance imaging, and optic glioma was found in 21% of the patients. P100 latencies were significantly longer in the patient group than in the control group (p = 0.013, p = 0.043). Patients with optic glioma were found to have significantly longer P100 latencies than patients without optic glioma, consistent with the anatomical location of the optic glioma (p = 0.042, p = 0.025). Conclusion: With this study, it has been shown that the P-VEP test is an objective electrophysiological test that can be used in the functional assessment of visual pathways in children with NF Type 1. We think that the use of the P-VEP test in the clinical follow-up of children with NF Type 1 may be particularly useful in the early detection of optic gliomas.Öğe Neurological findings spectrum in Celiac disease(TURKISH J PEDIATRICS, 2016) Aksoy, Erhan; Tiras-Teber, Serap; Kansu, Aydan; Deda, Gulhis; Kartal, AyseWe aimed to provide early diagnosis by determining possible Celiac disease related subclinical or symptomatic neurological abnormalities in children in order to decrease risk of mortality and morbidity. Children with Celiac disease were assessed with neurological examination, neurophysiological tests and neuroimaging. A total of 65 patients were included in the study. The neurological examination was abnormal in 4 patients. There were EEG abnormalities in 5 patients, VEP was abnormal in 7 patients, BAER was abnormal in 1 patient, ENMG was abnormal in 8 patients, and there were abnormal findings on neuroimaging in 2 patients. The Celiac disease related neurological complications that manifest in adulthood usually lay their foundations in childhood. Therefore, it must be kept in mind that subclinical neurological abnormalities may be related to Celiac disease, and Celiac disease may be the underlying cause in the patients with overt neurological abnormalities in childhood.Öğe Use of Complementary and Alternative Medicine Practices in Patients Admitted to the Pediatric Neurology Outpatient Clinic(Selçuk Üniversitesi, 2023 Haziran) Ceylan, Nesrin; Çelik, Halil; Özdemir, Mehmet Akif Fatih; Aksoy, Erhan; Atasoy, Ergin; Yüksel, Deniz; Öztoprak, UlkuIntroduction: Despite the developments in pharmacologic treatments, traditional and complementary therapies have recently gained popularity in our country, as well as around the world. Aim: To investigate complementary and alternative medicine practices (CAMP) during clinical visits of pediatric neurology patients, to raise awareness of families and patients about the use of complementary and alternative medicine, and to prevent possible negative interactions. Methods: This prospective survey study was conducted with the parents of 300 pediatric patients aged between 6 months and 18 years, who were being treated at the Child Neurology Clinic between March 1st and May 30th, 2020. For the study, 360 patients’ parents who came to the Pediatric Neurology Clinic for treatment were randomly selected, and a face-to-face survey lasting 2 minutes was conducted with the parents of 300 patients who agreed to participate in the study. This study was approved with the decision number E-20-12-62 at the meeting dated 21.12.2020 of the Clinical Research Ethics Committee of SBU Ankara Dr Sami Ulus Gynecology and Childhood Health and Diseases Training and Research Hospital. Results: Three hundred parents (56% women) participated in the study. Just over half (55.3%) of the patients were followed up with a diagnosis of epilepsy, 56.6% of the parents stated that they had used traditional and complementary therapy methods before, 43.4% stated that they did not use them, 46.54% stated that they said prayers and 23.9% used vitamin methods, respectively. When four different independent variables were examined separately, only the education level of the patient’s fathers was statistically significant (Wald= 4.102, p=0.043) Conclusion: This result shows that as the education level of the patient’s father increases, the probability of using traditional and complementary therapies applications decreases. In neurologic diseases, parents use traditional and complementary therapies as treatment methods, creating an alternative to modern medicine. Families and patients should be informed by investigating the reasons and frequency of using traditional and complementary therapies, raising the awareness of parents, and determining the possible harm caused by traditional and complementary therapies.
