Yazar "Kilic, M." seçeneğine göre listele
Listeleniyor 1 - 7 / 7
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe The effect of acute swimming exercise on plasma leptin in rats(COMENIUS UNIV, 2012) Baltaci, A. K.; Vurucu, N.; Uzun, A.; Mogulkoc, R.; Kilic, M.Exercise is known to increase free fatty acid and glucose metabolism. In consideration of such physiological effects of leptin such as reducing food intake and increasing energy consumption, many researchers have studied the relation between leptin and exercise. Despite the inconsistency between results, it is generally accepted that physical activity causes changes in leptin secretion. The present study aims to determine the changes that occur in plasma leptin levels of the rats subjected to acute swimming exercise, immediately after exercise, and in the 24th and 48th hours following exercise. Forty adult male rats of Sprague Dawley species were equally allocated to 4 groups. Group 1: General Control Group. Group 2: Swimming Group, the group that was decapitated just after 30-minutes of acute swimming exercise. Group 3: Swimming Group, the group that was decapitated 24 hours after 30-minutes of acute swimming exercise. Group 4: Swimming Group, the group that was decapitated 48 hours after 30-minutes of acute swimming exercise. Plasma leptin levels of the experimental animals were determined according to RIA method in the blood samples collected by decapitation method. Comparison of plasma leptin levels between groups revealed that the Group 3 had the highest plasma leptin levels (p < 0.01). Plasma leptin levels in the Group 1 (control) and 4 were not different and the Group 2 had the lowest plasma leptin levels (p < 0.01). Results of the present study show that an acute swimming exercise and/or stress factors associated with an acute exercise inhibit leptin secretion from the adipose tissue (Tab. 1, Ref. 21). Full Text in PDF www.elis.sk.Öğe The effect of acute swimming exercise on plasma melatonin levels in rats(COMENIUS UNIV, 2012) Uzun, A.; Baltaci, A. K.; Kilic, M.; Mogulkoc, R.Background: This study aims to determine the changes in plasma melatonin levels of rats performing acute swimming exercise, immediately following the exercise and after 24 and 48 hours. Methods: The study included 40 Sprague Dawley species adult male rats divided in to 4 groups as follows: group 1: general control group, group 2: swimming group A, the animales were decapitated after performing 30-minute acute swimming exercise, group 3: sSwimming group B, the animals were decapitated 24 hours after performing 30-minute acute swimming exercise and group 4: swimming group C, the animals were decapitated 48 hours after performing 30-minute acute swimming exercise. Blood samples were collected from all experimental animals by decapitation method and plasma melatonin levels were determined according to RIA method. Results: The comparison of plasma melatonin levels among groups revealed that group 3 had the highest plasma melatonin levels (p<0.01). The levels in group 1 (control) and group 4 were not different. The lowest plasma melatonin levels were found in group 2 (p<0.01). Conclusion: The results of our study demonstrate that plasma melatonin levels that decrease immediately after acute swimming exercise increase significantly after 24 hours and restore to resting levels after 48 hours (Tab. 1, Ref. 15). Full Text in PDF www.elis.sk.Öğe Effects of cooling on histamine-induced contractions of human umbilical artery: The role of ion channels(PROUS SCIENCE, SA, 2007) Atalik, K. E.; Kilic, M.; Nurullahqlu, Z. U.; Dogan, N.The effects of cooling (to 28 degrees C) on histamine (10(-9) - 3 x 10(-4) M)-induced contractions and the role of calcium (Ca2+), potassium (K-Ca(2+)) and sodium (Na+) channel blockers in the cooling-induced responses were investigated in the endothelium-denuded human umbilical artery. Concentration-response curves to histamine were isometrically recorded at 37 and 28 degrees C (control). The same procedure was repeated at 28 degrees C in the presence of tetraethylammonium (TEA, 10(-3) M), pilsicainide (10(-6) M), ouabain (10-6 M), caffeine (3 X 10-4 M), verapamil (10(-6) M) and also in Ca2+-free medium with ethylene glycol bis-(beta-aminoethyl ether) N,N,N-1,N-1-tetraacetic acid (EGTA). During cooling, the sensitivity, but not the maximal response, was significantly higher than 37 degrees C. Cooling to 28 degrees C after treatment with verapamil or pilsicainide decreased the sensitivity, whereas treatment with TEA and ouabain significantly increased sensitivity. Treatment with caffeine did not modify the effect of cooling. Furthermore, cooling to 28 degrees C after incubation in Ca(2+)free solution with EGTA decreased the sensitivity to histamine. The results of this study suggest the role of Ca2+, K-Ca(2+) and Na+-ion channels in the cooling-induced changes of human umbilical arteries treated with histamine. (C) 2007 Prous Science. All rights reserved.Öğe The prevalences of allergic diseases in rural and urban areas are similar(ELSEVIER ESPANA SLU, 2011) Guner, S. N.; Gokturk, B.; Kilic, M.; Ozkiraz, S.Background: In this study, we aimed to detect the influence of environmental and socioeconomic factors for asthma, allergic rhinitis, and eczema among children aged 6-18 years. Method: Two each of schools located in urban and in rural areas were included in the study. Children in these schools were asked to respond to 32 questions in total, including demographic and socioeconomic features and the questions of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire form. Results: The average age of children included in the study was 11.5 +/- 3.3 years, and the ratio of boys (55.4%) to girls (44.6%) was 1.2/1. The prevalence of asthma was found as 11.5%, allergic rhinitis as 22.1%, and eczema as 10.7%. Asthma (21.9%), allergic rhinitis (44.3%) and eczema (19.8%) were more frequent in cases which had family history of atopy (p < 0.001). Although there were differences between regions regarding income and educational levels, number of persons in the household, duration of breast feeding, and dietary habits, these variants were found inconclusive for the development of asthma. The risk of progression to asthma and atopic diseases decreased as age increased and the educational level of the father increased. Conclusion: According to our results, atopic diseases can be considered frequent in Konya, history of atopy in the family is the most predictive factor and the effects of rural or urban factors are not obvious in atopic disease development. (C) 2010 SEICAP. Published by Elsevier Espana, S.L. All rights reserved.Öğe The reliability and validity of the Turkish version of a childhood asthma control test(WILEY-BLACKWELL, 2011) Soyer, Uysal O.; Keskin, O.; Uzuner, N.; Yazicioglu, M.; Kilic, M.; Artac, H.; Ozmen, S.[Abstract not Available]Öğe Role of the nitric oxide on diazoxide-induced relaxation of the calf cardiac vein and coronary artery during cooling(WILEY-BLACKWELL PUBLISHING, INC, 2009) Atalik, K. E.; Kilic, M.; Dogan, N.The effects of cooling (to 28 degrees C) on the vasodilation induced by diazoxide (10(-9)-3 x 10(-4) m) on carbachol-pre-contracted calf cardiac vein and coronary artery and the role of nitric oxide in these effects were analyzed. Diazoxide produced concentration-dependent relaxation of calf cardiac vein and coronary artery rings pre-contracted with carbachol (10(-6) m). During cooling, the pIC(50) values, but not the maximal responses, to diazoxide were significantly lower than at 37 degrees C in both preparations. Cooling to 28 degrees C in the presence of N(G)-nitro-L-arginine methyl ester (10(-4) m) did not modify the effect of temperature both in cardiac vein and coronary artery. These results suggest that cooling-induced changes of diazoxide in calf cardiac vein and coronary artery are independent of nitric oxide.Öğe The Utility of Childhood Asthma Control Test and its Relationship with Control Measures and with the Decisions Made by Asthma Specialist(MOSBY-ELSEVIER, 2010) Sekerel B, E.; Keskin, O.; Uzuner, N.; Yazicioglu, M.; Kilic, M.; Artac, H.; Ozmen, S.[Abstract not Available]
